{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:33:33Z","timestamp":1771623213217,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1969,5,1]],"date-time":"1969-05-01T00:00:00Z","timestamp":-21168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1969,5]]},"abstract":"<jats:p>1. Intracellular records were obtained from ganglion cells of the pelvic plexus of male guinea\u2010pigs.<\/jats:p><jats:p>2. The input resistance of cells which responded to intracellular stimulation varied from 40 to 150 M\u03a9. Slope resistance decreased when the membrane was hyperpolarized. Time constants varied from 5 to 200 msec. Resting membrane potentials ranged from 40 to 70 mV.<\/jats:p><jats:p>3. Action potentials in response to direct stimulation were followed by a prolonged phase of after\u2010hyperpolarization.<\/jats:p><jats:p>4. A second type of cell was also impaled which did not respond to electrical stimulation. These cells had resting membrane potentials in the range 60\u201370 mV, input resistances of less than 20 M\u03a9 and time constants of less than 3 msec.<\/jats:p><jats:p>5. In most ganglion cells, stimulation of the hypogastric nerve evoked action potentials which were often followed by a secondary phase of depolarization indicating continuing transmitter action.<\/jats:p><jats:p>6. Orthodromic responses were generally \u2018all\u2010or\u2010nothing\u2019 and could not be graded with changes in stimulus strength. The latency of orthodromic responses indicated that ganglion cells were innervated by both B and C fibres in the hypogastric nerve.<\/jats:p><jats:p>7. Orthodromic responses were blocked by tubocurarine, 5 \u00d7 10<jats:sup>\u22125<\/jats:sup> g\/ml., and dihydro\u2010\u03b2\u2010erythroidine, 10<jats:sup>\u22125<\/jats:sup> g\/ml.<\/jats:p><jats:p>8. Spontaneous, excitatory post\u2010synaptic potentials of up to 4\u00b78 mV in amplitude were observed. The frequency of their discharge was greatly increased by repetitive stimulation of the hypogastric nerve.<\/jats:p><jats:p>9. The ultrastructure of the pelvic ganglia was studied by electronmicroscopy. Two types of ganglion cell process were observed, fine (0\u00b71 \u03bc) branching tufts thrown up from the soma within the surrounding capsule and longer, thicker (1 \u03bc) extracapsular processes. Synapses were found to occur most frequently between the varicose terminal segments of preganglionic axons and the small intracapsular processes.<\/jats:p><jats:p>10. Similarities between the properties of the pelvic ganglia innervated by the hypogastric nerve and those of the parasympathetic division of the autonomic nervous system are discussed.<\/jats:p>","DOI":"10.1113\/jphysiol.1969.sp008784","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T11:52:48Z","timestamp":1418989968000},"page":"723-743","source":"Crossref","is-referenced-by-count":66,"title":["Transmission from preganglionic fibres in the hypogastric nerve to peripheral ganglia of male guinea\u2010pigs"],"prefix":"10.1113","volume":"201","author":[{"given":"J. G.","family":"Blackman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Crowcroft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. E.","family":"Devine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mollie E.","family":"Holman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yonemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1969,5]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1969.sp008784","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1969.sp008784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T16:41:08Z","timestamp":1699461668000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1969.sp008784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,5]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1969,5]]}},"alternative-id":["10.1113\/jphysiol.1969.sp008784"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1969.sp008784","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,5]]}}}