{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T03:39:47Z","timestamp":1767843587384,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1971,5,1]],"date-time":"1971-05-01T00:00:00Z","timestamp":41904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1971,5]]},"abstract":"<jats:p>1. Transfer of endogenous \u03b1\u2010amino nitrogen from the maternal to foetal side of the placental membrane was studied in the foetal guinea\u2010pig placenta perfused, <jats:italic>in situ<\/jats:italic> via the umbilical vessels, with an artificial fluid. Changes in maternal placental blood flow were followed by measuring the transfer of antipyrine into the perfusate.<\/jats:p><jats:p>2. Active transport by the membrane was demonstrated under these conditions by observing the increased ratio of \n<jats:sc>L\/D<\/jats:sc> leucine appearing in the perfusate in comparison with the maternal plasma ratio.<\/jats:p><jats:p>3. Reduction in maternal placental flow following haemorrhage was associated with a fall in transfer of amino nitrogen to about half of the control values.<\/jats:p><jats:p>4. The concentration of \u03b1\u2010amino nitrogen in the perfusate was inversely proportional to the foetal placental flow which had a smaller influence on amino nitrogen transfer per min than did the maternal blood flow.<\/jats:p><jats:p>5. Hypoxia and some inhibitors of oxidative metabolism were without influence on the transfer of \u03b1\u2010amino nitrogen in this preparation.<\/jats:p>","DOI":"10.1113\/jphysiol.1971.sp009450","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T11:08:53Z","timestamp":1418987333000},"page":"583-597","source":"Crossref","is-referenced-by-count":30,"title":["The transfer of free \u03b1\u2010amino nitrogen across the placental membrane in the guinea\u2010pig"],"prefix":"10.1113","volume":"214","author":[{"given":"Margaret L.","family":"Reynolds","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1971,5]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1971.sp009450","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1971.sp009450","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T09:22:20Z","timestamp":1699435340000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1971.sp009450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,5]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1971,5]]}},"alternative-id":["10.1113\/jphysiol.1971.sp009450"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1971.sp009450","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,5]]}}}