{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:28:47Z","timestamp":1758475727552},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1972,3,1]],"date-time":"1972-03-01T00:00:00Z","timestamp":68256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1972,3]]},"abstract":"<jats:p>1. Using a double\u2010lumen tube perfusion system the rates of absorption of \n<jats:sc>L<\/jats:sc>\u2010methionine and glucose from a 30 cm segment of the jejunum were estimated in eight relatively normal Zambian African subjects. The effect of each substrate on the absorption of the other has also been investigated. The solutions perfused were given at 12\u00b70 ml. min<jats:sup>\u22121<\/jats:sup>, and contained (<jats:italic>A<\/jats:italic>) 100 m\u2010mole l.<jats:sup>\u22121<\/jats:sup> \n<jats:sc>L<\/jats:sc>\u2010methionine, (<jats:italic>B<\/jats:italic>) 100 m\u2010mole l.<jats:sup>\u22121<\/jats:sup> \n<jats:sc>L<\/jats:sc>\u2010methionine and 150 m\u2010mole l.<jats:sup>\u22121<\/jats:sup> glucose and (<jats:italic>C<\/jats:italic>) 150 m\u2010mole l.<jats:sup>\u22121<\/jats:sup> glucose.<\/jats:p><jats:p>2. The presence of glucose in the perfusing fluid did not significantly alter the mean absorption rate of methionine; in six subjects, the rate of methionine absorption from solution <jats:italic>B<\/jats:italic> was less than from solution <jats:italic>A<\/jats:italic>, but in two there was a marked difference in the opposite direction. This may indicate an individual difference in the effect of glucose on \n<jats:sc>L<\/jats:sc>\u2010methionine absorption in man. The presence of methionine in the perfusing fluid did not significantly alter the mean absorption rate of glucose.<\/jats:p><jats:p>3. Five subjects had a transitory psychiatric disturbance after the investigation. The cause of this is not clear, but was probably caused by the absorption of a break\u2010down product of methionine from the large intestine.<\/jats:p>","DOI":"10.1113\/jphysiol.1972.sp009777","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T10:33:51Z","timestamp":1418985231000},"page":"707-714","source":"Crossref","is-referenced-by-count":7,"title":["Intestinal absorption rate of L\u2010methionine in man and the effect of glucose in the perfusing fluid"],"prefix":"10.1113","volume":"221","author":[{"given":"G. C.","family":"Cook","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1972,3]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1972.sp009777","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1972.sp009777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T13:23:28Z","timestamp":1699449808000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1972.sp009777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1972,3]]}},"alternative-id":["10.1113\/jphysiol.1972.sp009777"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1972.sp009777","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,3]]}}}