{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:13:49Z","timestamp":1791288829205,"version":"4.3.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1977,12,1]],"date-time":"1977-12-01T00:00:00Z","timestamp":249782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1977,12]]},"abstract":"<jats:p>1. The responses of single neurones in the nuclei raph\u00e9s magnus, medianus, dorsalis and pontis to changes in skin temperature were recorded in rats anaesthetized with urethane. Skin temperature was altered by means of a water\u2010perfused jacket. 2. Of 210 neurones studied, thirty\u2010five were specifically excited by warming the skin whilst twenty were cold responsive. The greatest proportion of cells responding to skin temperature were in the nucleus raph\u00e9 magnus, whilst few neurones in the raph\u00e9 dorsalis and pontis were influenced. 3. The warm units had peak activity at a mean skin temperature of 37.7 degrees C whilst the cold cells had a corresponding maximal rate at 29.0 degreet C. Mechanical and noxious peripheral stimulation, blood pressure changes and temperatures other than that of skin did not affect the neurones. 4. The neurones influenced by skin temperature were histologically verified as being within the raph\u00e9 system. 5. LSD inhibited all neurones tested, indicating that the cells were serotonergic. 6. The responses to skin temperature were unchanged in rats with midcollicular sections suggesting an ascending thermal system. 7. The results suggest that any involvement of 5\u2010HT in central thermo\u2010regulation is in terms of an afferent thermal pathway mediated by serotonergic raph\u00e9 neurones.<\/jats:p>","DOI":"10.1113\/jphysiol.1977.sp012094","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T08:15:35Z","timestamp":1418976935000},"page":"277-293","source":"Crossref","is-referenced-by-count":92,"title":["Specific responses of rat raph\u00e9 neurones to skin temperature."],"prefix":"10.1113","volume":"273","author":[{"given":"A H","family":"Dickenson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1977,12]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1977.sp012094","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1977.sp012094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T05:46:27Z","timestamp":1699249587000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1977.sp012094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,12]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1977,12]]}},"alternative-id":["10.1113\/jphysiol.1977.sp012094"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1977.sp012094","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,12]]}}}