{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T23:24:36Z","timestamp":1705274676488},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1983,12,1]],"date-time":"1983-12-01T00:00:00Z","timestamp":439084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1983,12]]},"abstract":"<jats:p>Intracellular potentials were recorded with micropipettes from hair cells with free\u2010standing stereocilia in the cochleae of anaesthetized alligator lizards. Wave forms of intracellular responses to click stimuli were classified into three types: hair cells, supporting cells, and untuned cells. We studied primarily the responses of hair cells to tonal stimuli. For most frequencies, f, and levels, P, of tone\u2010burst stimuli, the response envelope of the receptor potential increases monotonically at the tone\u2010burst onset, and decreases monotonically at tone\u2010burst offset. Overshoot in the envelope of the response at the onset and offset of tone bursts is observed only for tone bursts of low f, high P, and short (approximately equal to 1 msec) rise\/fall time. The steady\u2010state response to tones consists of a positive (depolarizing) d.c. component, V0, plus a.c. components (e.g. a fundamental component, V1, second harmonic, V2, and third harmonic, V3). The magnitudes of a.c. and d.c. components are functions of f and P, and show three characteristics: frequency selectivity, non\u2010linearity, and low\u2010pass filtering. The receptor potential is frequency selective. The frequency selectivity of V0 and V1 components was measured by means of iso\u2010voltage (iso\u2010V0 and iso\u2010V1) contours. Iso\u2010V0 and iso\u2010V1 contours are V\u2010shaped: the maximum sensitivity occurs at a characteristic frequency (c.f.). The shapes of these contours near the c.f. depend on the values of V0 and V1 at which the contours were measured and are sharper for lower values of V0 and V1. The mean slopes of the low\u2010 and high\u2010frequency sides of these contours are: \u201045.0 and +85.1 dB\/decade for iso\u2010V0 contours (n = 26), and \u201033.6 and +103.8 dB\/decade for iso\u2010V1 contours (n = 28). The receptor potential has non\u2010linear properties. The magnitudes and phase angles of V0, V1, V2, and V3 receptor\u2010potential components were measured as a function of P for different f. The slopes of level functions (the dependence of log V0 and log magnitude of V1 on log P) were measured at low levels for different f. For values of f differing from c.f. by more than a half\u2010octave, the slope for V0 is between 1 and 2 with a mean of 1.3; the slope for V1 is about 1, i.e. magnitude of V1 increases approximately linearly with P. For frequencies near c.f., the slopes for V0 and V1 are approximately 0.8 and 0.5, respectively, indicating the presence of a compressive non\u2010linearity.(ABSTRACT TRUNCATED AT 400 WORDS)<\/jats:p>","DOI":"10.1113\/jphysiol.1983.sp014975","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T06:53:21Z","timestamp":1418972001000},"page":"205-240","source":"Crossref","is-referenced-by-count":39,"title":["Receptor potentials of lizard cochlear hair cells with free\u2010standing stereocilia in response to tones."],"prefix":"10.1113","volume":"345","author":[{"given":"T","family":"Holton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T F","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,12]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1983.sp014975","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1983.sp014975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T08:39:12Z","timestamp":1697791152000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1983.sp014975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,12]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,12]]}},"alternative-id":["10.1113\/jphysiol.1983.sp014975"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1983.sp014975","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,12]]}}}