{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:31:06Z","timestamp":1771630266446,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:p>The intrinsic motility of the reticulo\u2010rumen was studied by electromyography in nineteen sheep subjected to bilateral thoracic vagotomy and maintained by intragastric infusion of a complete liquid diet. The influences of distension, temperature and tactile and chemical stimuli on the intrinsic reticulo\u2010ruminal motility were investigated. The level of electrical discharge in the reticulum and rumen in the first 3 days after vagotomy was increased progressively with distension without giving rise to the large group discharges characteristic of the long\u2010term vagotomized sheep, and was reduced by atropine (0.1\u20101 mg kg\u20101) but not by hexamethonium (2 mg kg\u20101). In the long\u2010term vagotomized animals, the frequency of the large group discharges over the reticulo\u2010rumen varied with the degree of reticulo\u2010ruminal distension. The discharges were absent below a threshold rumen volume; above the threshold they increased progressively with volume until a maximal rate of six to seven regular discharges per minute was established at large ruminal volumes. The discharges were abolished by atropine (0.1\u20101 mg kg\u20101) or hexamethonium (2 mg kg\u20101). With the rumen volume below the threshold, in all areas of the reticulo\u2010rumen localized distension stimulated local discharge only and did not induce large group discharge. Replacement of rumen contents with an equal volume of 0.2 M\u2010acetic, \u2010propionic or \u2010butyric acid buffered to pH 4.0 rapidly abolished the large group discharges over the entire reticulo\u2010rumen. Replacement of rumen contents by an equal volume of 0.9% NaCl at 30 degrees C immediately abolished the large group discharges; at temperatures between 35 and 43 degrees C this had no effect. Gentle tactile stimulation increased local discharge in the reticulum and cranial dorsal sac but not in other areas of the rumen and did not affect large group discharge in any region. It is concluded that the intrinsic reticulo\u2010ruminal motility of chronically vagotomized sheep is principally regulated by the degree of reticulo\u2010ruminal distension. Like the C.N.S.\u2010controlled motility of the vagus\u2010intact sheep it is inhibited by high concentrations of volatile fatty acids. Local control mechanisms therefore may interact with central control in the over\u2010all regulation of motility in vagus\u2010intact sheep.<\/jats:p>","DOI":"10.1113\/jphysiol.1984.sp015029","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T06:51:47Z","timestamp":1418971907000},"page":"379-393","source":"Crossref","is-referenced-by-count":21,"title":["Control of intrinsic reticulo\u2010ruminal motility in the vagotomized sheep."],"prefix":"10.1113","volume":"346","author":[{"given":"P C","family":"Gregory","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,1]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1984.sp015029","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1984.sp015029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T21:02:44Z","timestamp":1697749364000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1984.sp015029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.1113\/jphysiol.1984.sp015029"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1984.sp015029","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}