{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T08:55:04Z","timestamp":1774342504335,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1987,11,1]],"date-time":"1987-11-01T00:00:00Z","timestamp":562723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1987,11]]},"abstract":"<jats:p>1. Smooth muscle from cat small intestine shows two types of spontaneous slow electrical waves in the frequency range of 10\u201015 min\u20101. One type of slow wave is a ouabain\u2010sensitive, atropine\u2010insensitive spontaneous oscillation. The other type of wave can be induced by acetylcholine (ACh), is blocked by atropine, and is not blocked by ouabain. 2. Ouabain\u2010sensitive slow waves rise directly from the baseline, are near sinusoidal and may or may not have spikes. ACh\u2010induced waves have pre\u2010potentials, are usually topped by spikes and show after\u2010hyperpolarization. 3. The two types of rhythmic wave differ in ionic and metabolic requirements and drug sensitivity. Ouabain\u2010sensitive waves occur only in intestinal muscle attached to a boundary layer containing interstitial cells; ACh\u2010induced waves can occur in strips of muscle lacking boundary cells. 4. Na+ pump inhibitors ouabain, cold and K+\u2010free solution, reduce amplitude but not frequency of ouabain\u2010sensitive slow waves. 5. The ACh\u2010induced waves require higher extracellular concentrations of Na+ and Ca2+ and can occur in preparations in Li+\u2010Krebs solution; the ouabain\u2010sensitive rhythm persists in lower concentrations of Na+ and Ca2+ and is not supported by Li+. The ouabain\u2010sensitive waves are more sensitive to cyanide and less sensitive to cooling than the ACh\u2010induced waves. 6. Guinea\u2010pig intestine shows only one type of rhythmic wave, which is atropine sensitive and resembles in shape the ACh\u2010induced wave of other species. Ouabain increases the frequency of the guinea\u2010pig rhythm. 7. It is concluded that intestinal muscle of most mammals, but not of guinea\u2010pig, is capable of two types of slow electrical rhythms.<\/jats:p>","DOI":"10.1113\/jphysiol.1987.sp016769","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T06:39:20Z","timestamp":1418971160000},"page":"51-69","source":"Crossref","is-referenced-by-count":13,"title":["Two types of 'slow waves' in intestinal smooth muscle of cat."],"prefix":"10.1113","volume":"392","author":[{"given":"V","family":"Dahms","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C L","family":"Prosser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1987,11]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1987.sp016769","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1987.sp016769","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T04:20:36Z","timestamp":1697862036000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1987.sp016769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,11]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,11]]}},"alternative-id":["10.1113\/jphysiol.1987.sp016769"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1987.sp016769","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,11]]}}}