{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:17:29Z","timestamp":1761059849694},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1987,12,1]],"date-time":"1987-12-01T00:00:00Z","timestamp":565315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1987,12]]},"abstract":"<jats:p>1. The involvement of calcium in the regulation of iodide secretion was investigated in stripped sheets of rat small intestine. 2. In the absence of exogenous modifiers a net iodide absorption was observed in the rat proximal intestine, whereas the mid\u2010intestine secreted iodide. 3. Removal of Ca2+ from the bathing solutions abolished net I\u2010 secretion in the mid\u2010intestine. The calcium channel blocker verapamil produced similar effects on net I\u2010 secretion. 4. Theophylline increased net I\u2010 secretion both in the absence and in the presence of verapamil, but the effects of theophylline were less in the presence of verapamil or in Ca2+\u2010free media. 5. Trifluoperazine inhibited basal iodide secretion and attenuated theophylline\u2010induced I\u2010 secretion. 6. All the modifiers which prevented net I\u2010 secretion reduced iodide fluxes across the mucosal border and increased serosal iodide exit. The opposite was observed with theophylline. 7. It is suggested that I\u2010 secretion might result from changes in both mucosal and serosal I\u2010 permeabilities, and that both processes appear to be regulated by calmodulin.<\/jats:p>","DOI":"10.1113\/jphysiol.1987.sp016807","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T06:39:20Z","timestamp":1418971160000},"page":"19-27","source":"Crossref","is-referenced-by-count":5,"title":["Iodide transport in rat small intestine: dependence on calcium."],"prefix":"10.1113","volume":"393","author":[{"given":"A","family":"Ilundain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Larralde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Toval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1987,12]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1987.sp016807","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1987.sp016807","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T07:12:48Z","timestamp":1697872368000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1987.sp016807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,12]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,12]]}},"alternative-id":["10.1113\/jphysiol.1987.sp016807"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1987.sp016807","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,12]]}}}