{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:07:12Z","timestamp":1698642432187},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1988,6]]},"abstract":"<jats:p>1. Standard renal clearance techniques were used to investigate the effects of 2.5, 5 and 10% D\u2010glucose, 2.5% 2\u2010deoxy\u2010D\u2010glucose and 2.5% D\u2010xylose on kidney function in male rats. 2. There was no consistent effect of D\u2010glucose on urinary sodium output except with 10% D\u2010glucose, where sodium excretion was raised compared to controls. 3. An increased urinary calcium output was seen in all D\u2010glucose\u2010infused rats compared to controls. Values obtained for 2.5, 5 and 10% glucose were respectively 32, 61 and 58% above control data. Neither 2\u2010deoxy\u2010D\u2010glucose nor D\u2010xylose produced a calciuresis. 4. The increased urinary calcium excretion in D\u2010glucose rats was the result of a reduction in fractional calcium reabsorption. Glomerular filtration rate (GFR) was unchanged. It was not dependent upon glycosuria or a diuresis.<\/jats:p>","DOI":"10.1113\/jphysiol.1988.sp017131","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T06:35:35Z","timestamp":1418970935000},"page":"447-458","source":"Crossref","is-referenced-by-count":7,"title":["Effects of D\u2010glucose, 2\u2010deoxy\u2010D\u2010glucose and D\u2010xylose on renal function in the rat."],"prefix":"10.1113","volume":"400","author":[{"given":"H O","family":"Garland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H J","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1988,6]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1988.sp017131","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1988.sp017131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T03:14:39Z","timestamp":1697858079000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1988.sp017131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["10.1113\/jphysiol.1988.sp017131"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1988.sp017131","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6]]}}}