{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:24:21Z","timestamp":1754483061712},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T00:00:00Z","timestamp":1083628800000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:p>We tested the hypothesis that in humans, carotid\u2010baroreflex dynamic responses (evaluated by examining the time course of the carotid\u2010baroreflex\u2010induced alterations in muscle sympathetic nerve activity (MSNA), mean arterial blood pressure (MAP) and heart rate (HR)) would be altered during mild orthostatic stress in ways that serve to limit orthostatic hypotension. In 12 healthy subjects (10 male, 2 female), 5\u2010s periods of neck pressure (NP) (50 mmHg) and neck suction (NS) (\u2212 60 mmHg) were used to evaluate carotid baroreflex function at rest (CON) and during lower body negative pressure (LBNP) (\u221215 mmHg). During LBNP (as compared with CON) (a) the augmentations in MSNA and MAP elicited by NP were greater, (b) the NS\u2010induced period of MSNA suppression was, if anything, shorter, (c) the peak decrement in MAP elicited by NS, although not different in amplitude, occurred earlier and recovered to its initial level more quickly after NS, and (d) the HR responses to NP and NS were greater. These results suggest that during mild orthostatic stress, carotid\u2010baroreflex dynamic responses are modulated in ways that should help maintain blood pressure and limit orthostatic hypotension.<\/jats:p>","DOI":"10.1113\/jphysiol.2003.057133","type":"journal-article","created":{"date-parts":[[2004,3,9]],"date-time":"2004-03-09T01:43:51Z","timestamp":1078796631000},"page":"321-330","source":"Crossref","is-referenced-by-count":25,"title":["Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans"],"prefix":"10.1113","volume":"557","author":[{"given":"Masashi","family":"Ichinose","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asami","family":"Kitano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narihiko","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Nishiyasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,5,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1981.sp013604"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1977.tb10383.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1972.tb05157.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014647"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.47.2.208"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/oso\/9780198576938.003.0005","volume-title":"Human Baroreflexes in Health and Disease","author":"Eckberg DL","year":"1992"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1152\/jappl.1987.63.6.2325","article-title":"Isometric exercise modifies autonomic baroreflex responses in humans","volume":"63","author":"Eckberg DL","year":"1987","journal-title":"J Appl Physiol"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2001.280.3.H1383"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(80)90098-2"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1991.260.3.R635"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.024794"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.34.4.515"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.5.1979"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.37.4.422"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1998.274.3.H901"},{"key":"e_1_2_5_17_1","first-page":"755","volume-title":"Handbook of Physiology, section 2, the Cardiovascular System, vol. 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