{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:56:04Z","timestamp":1790175364933,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,6,24]],"date-time":"2004-06-24T00:00:00Z","timestamp":1088035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:p>That muscular blood flow may reach 2.5 l kg<jats:sup>\u22121<\/jats:sup> min<jats:sup>\u22121<\/jats:sup> in the quadriceps muscle has led to the suggestion that muscular vascular conductance must be restrained during whole body exercise to avoid hypotension. The main aim of this study was to determine the maximal arm and leg muscle vascular conductances (VC) during leg and arm exercise, to find out if the maximal muscular vasodilatory response is restrained during maximal combined arm and leg exercise. Six Swedish elite cross\u2010country skiers, age (mean \u00b1<jats:sc>s.e.m.<\/jats:sc>) 24 \u00b1 2 years, height 180 \u00b1 2 cm, weight 74 \u00b1 2 kg, and maximal oxygen uptake <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/TJP_306_mu1.gif\" xlink:title=\"inline image\"\/> 5.1 \u00b1 0.1 l min<jats:sup>\u22121<\/jats:sup> participated in the study. Femoral and subclavian vein blood flows, intra\u2010arterial blood pressure, cardiac output, as well as blood gases in the femoral and subclavian vein, right atrium and femoral artery were determined during skiing (roller skis) at \u223c76% of <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/TJP_306_mu2.gif\" xlink:title=\"inline image\"\/> and at <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/TJP_306_mu3.gif\" xlink:title=\"inline image\"\/> with different techniques: diagonal stride (combined arm and leg exercise), double poling (predominantly arm exercise) and leg skiing (predominantly leg exercise). During submaximal exercise cardiac output (26\u201327 l min<jats:sup>\u22121<\/jats:sup>), mean blood pressure (MAP) (\u223c87 mmHg), systemic VC, systemic oxygen delivery and pulmonary <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/TJP_306_mu4.gif\" xlink:title=\"inline image\"\/> (\u223c4 l min<jats:sup>\u22121<\/jats:sup>) attained similar values regardless of exercise mode. The distribution of cardiac output was modified depending on the musculature engaged in the exercise. There was a close relationship between VC and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/TJP_306_mu5.gif\" xlink:title=\"inline image\"\/> in arms (<jats:italic>r<\/jats:italic>= 0.99, <jats:italic>P<\/jats:italic> &lt; 0.001) and legs (<jats:italic>r<\/jats:italic>= 0.98, <jats:italic>P<\/jats:italic> &lt; 0.05). Peak arm VC (63.7 \u00b1 5.6 ml min<jats:sup>\u22121<\/jats:sup> mmHg<jats:sup>\u22121<\/jats:sup>) was attained during double poling, while peak leg VC was reached at maximal exercise with the diagonal technique (109.8 \u00b1 11.5 ml min<jats:sup>\u22121<\/jats:sup> mmHg<jats:sup>\u22121<\/jats:sup>) when arm VC was 38.8 \u00b1 5.7 ml min<jats:sup>\u22121<\/jats:sup> mmHg<jats:sup>\u22121<\/jats:sup>. If during maximal exercise arms and legs had been vasodilated to the observed maximal levels then mean arterial pressure would have dropped at least to 75\u201377 mmHg in our experimental conditions. It is concluded that skeletal muscle vascular conductance is restrained during whole body exercise in the upright position to avoid hypotension.<\/jats:p>","DOI":"10.1113\/jphysiol.2003.059287","type":"journal-article","created":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T00:58:43Z","timestamp":1083632323000},"page":"319-331","source":"Crossref","is-referenced-by-count":183,"title":["Maximal muscular vascular conductances during whole body upright exercise in humans"],"prefix":"10.1113","volume":"558","author":[{"given":"J. A. L.","family":"Calbet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Jensen\u2010Urstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Van Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010C.","family":"Holmberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Rosdahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Saltin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,6,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1152\/jappl.1991.70.2.928","article-title":"Arm blood flow at rest and during arm exercise","volume":"70","author":"Ahlborg G","year":"1991","journal-title":"J Appl Physiol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1985.59.5.1647"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1985.sp015794"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00155.2002"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200110000-00011"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1152\/ajplegacy.1973.225.3.675","article-title":"Central and peripheral circulatory changes after training of the arms or legs","volume":"225","author":"Clausen JP","year":"1973","journal-title":"Am J Physiol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000065225.18093.E4"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000049746.29175.3F"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2001.0331l.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(78)90665-3"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1997.82.5.1573"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1970.29.1.82"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.1992.tb00352.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1152\/jappl.1990.68.4.1453","article-title":"Blood flow to contracting human muscles: influence of increased sympathetic activity","volume":"68","author":"Joyner MJ","year":"1990","journal-title":"J Appl Physiol"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.6.2586"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1959.39.2.183"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1999.87.6.2375"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-201x.2001.00796.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.278.1.H162"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1998.85.3.1194"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(90)90078-D"},{"key":"e_1_2_5_23_1","first-page":"H1545","article-title":"High muscle blood flows are not attenuated by recruitment of additional muscle mass","volume":"269","author":"Richardson RS","year":"1995","journal-title":"Am J Physiol"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.4.1911"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1999.276.2.H438"},{"key":"e_1_2_5_26_1","first-page":"87","article-title":"Some comparative aspects on the camel as a racing animal","volume":"617","author":"Rose RJ","year":"1994","journal-title":"Acta Physiol Scand Suppl"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.2.491"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1987.62.2.606"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00273.2002"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.034496"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.023556"}],"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.2003.059287","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.2003.059287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T19:22:34Z","timestamp":1697311354000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.2003.059287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6,24]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["10.1113\/jphysiol.2003.059287"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.2003.059287","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6,24]]}}}