{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:04:54Z","timestamp":1773421494156,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,11,23]],"date-time":"2004-11-23T00:00:00Z","timestamp":1101168000000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p>Carotid baroreflex (CBR) function was examined in five men and three women (25 \u00b1 1 years) using the variable\u2010pressure neck collar technique at rest and during dynamic, one\u2010legged knee extension exercise at 7 W and 25 W. The CBR exhibited control of leg vascular conductance (LVC) at rest and during exercise in both an exercising leg (EL) and a non\u2010exercising leg (NEL) across a wide range of pressures from +40 Torr neck pressure (NP) to \u221280 Torr neck suction (NS). Specifically, increases in LVC (% change) in response to NS were no different across \u221220 to \u221280 Torr in either EL or NEL compared to rest, <jats:italic>P<\/jats:italic> &gt; 0.05. However, CBR\u2010mediated decreases in percentage LVC in response to NP were attenuated in EL at both 7 W (16 \u00b1 1%) and 25 W (12 \u00b1 1%) compared to rest (40 \u00b1 3%; <jats:italic>P<\/jats:italic> &lt; 0.05) as well as compared to responses in the NEL (36 \u00b1 6% at 7 W and 36 \u00b1 7% at 25 W; <jats:italic>P<\/jats:italic> &lt; 0.05). This decrease in vascular responsiveness in EL was associated with a reduction in the gain of the percentage muscle sympathetic nerve activity (%MSNA)\u2013%LVC relationship compared to rest (<jats:italic>P<\/jats:italic> &lt; 0.05). Collectively, these data indicate that, despite a clear attenuation of the vascular response to MSNA in the exercising leg, CBR\u2010mediated changes in mean arterial pressure were no different between rest and exercise.<\/jats:p>","DOI":"10.1113\/jphysiol.2004.071944","type":"journal-article","created":{"date-parts":[[2004,9,24]],"date-time":"2004-09-24T00:14:39Z","timestamp":1095984879000},"page":"283-293","source":"Crossref","is-referenced-by-count":45,"title":["Carotid baroreflex control of leg vasculature in exercising and non\u2010exercising skeletal muscle in humans"],"prefix":"10.1113","volume":"561","author":[{"given":"David","family":"Melvin Keller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul 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