{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:24:19Z","timestamp":1790717059156,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T00:00:00Z","timestamp":1296172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:p><jats:bold>Abstract\u2002<\/jats:bold> Combining voltage and Ca<jats:sup>2+<\/jats:sup> imaging allows the correlation of electrical and chemical activity at sub\u2010cellular level. Here we describe a novel apparatus designed to obtain simultaneous voltage and Ca<jats:sup>2+<\/jats:sup> measurements with single\u2010trial resolution from sites as small as a few microns. These measurements can be obtained with negligible optical cross\u2010talk between the two signals and negligible photo\u2010damage of the preparation. The capability of the technique was assessed recording either from individual neurons in brain slices or from networks of cultured neurons. The present achievements open the gate to many novel physiological investigations requiring simultaneous measurement of voltage and Ca<jats:sup>2+<\/jats:sup> signals.<\/jats:p>","DOI":"10.1113\/jphysiol.2010.200220","type":"journal-article","created":{"date-parts":[[2010,11,30]],"date-time":"2010-11-30T05:04:41Z","timestamp":1291093481000},"page":"489-494","source":"Crossref","is-referenced-by-count":39,"title":["High\u2010resolution simultaneous voltage and Ca<sup>2+<\/sup> imaging"],"prefix":"10.1113","volume":"589","author":[{"given":"Kaspar E.","family":"Vogt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Gerharz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Canepari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,1,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01178.2006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004240050703"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.125005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004011"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-008-9285-y"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2010.01.024"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2009.184960"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.142315"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3451-08.2008"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/384170a0"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0270(94)00219-7"}],"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.2010.200220","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.2010.200220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T04:37:26Z","timestamp":1698727046000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.2010.200220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,28]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["10.1113\/jphysiol.2010.200220"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.2010.200220","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,28]]}}}