{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:48:18Z","timestamp":1791114498395,"version":"4.1.0"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T00:00:00Z","timestamp":1298592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p><jats:bold>Non\u2010technical summary\u2002<\/jats:bold> During pregnancy the uterus must maintain a low contractile state to permit growth of the fetus and inhibt premature delivery. We show uterine smooth muscle cells express specific potassium channels (called stretch\u2010dependent potassium channels; TREK\u20101). These channels are activated by stretch, stabilize resting membrane potentials of cells at negative potentials, and reduce excitability. During pregnancy the expression of TREK\u20101 channels increases, and this may contribute to reduced excitability. Near the onset of labour, TREK\u20101 expression declines, and this may promote the transition to a contractile state. Thus, our data suggest dynamic regulation of TREK\u20101 channel expression in the uterus contributes to the maintenance of pregnancy.<\/jats:p>","DOI":"10.1113\/jphysiol.2010.203869","type":"journal-article","created":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T03:55:07Z","timestamp":1294718107000},"page":"1221-1233","source":"Crossref","is-referenced-by-count":49,"title":["The stretch\u2010dependent potassium channel TREK\u20101 and its function in murine myometrium"],"prefix":"10.1113","volume":"589","author":[{"given":"Kevin","family":"Monaghan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salah A.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Dwyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William 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