{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:16:17Z","timestamp":1791173777328,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2011,7,15]],"date-time":"2011-07-15T00:00:00Z","timestamp":1310688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2011,7,15]]},"abstract":"<jats:p>\n                    <jats:bold>Non\u2010technical summary\u2002<\/jats:bold>\n                    Plasma potassium concentration is a major determinant of muscle contractility and nerve conduction. The maintenance of plasma potassium concentration depends on the ability of kidneys to daily secrete in the urine the exact quantity of potassium ingested in the food. We show that in nephrotic syndrome, a common disease featuring abnormal urinary protein excretion and sodium retention, the membrane protein called ROMK channel responsible for kidney potassium secretion is inhibited. Thus, nephrotic rats are unable to excrete a dietary load of potassium and develop hyperkalaemia. Based on these findings, we would recommend not only a low sodium diet but also a controlled potassium diet for patients with nephrotic syndrome.\n                  <\/jats:p>","DOI":"10.1113\/jphysiol.2011.209692","type":"journal-article","created":{"date-parts":[[2011,5,23]],"date-time":"2011-05-23T22:29:13Z","timestamp":1306189753000},"page":"3611-3621","source":"Crossref","is-referenced-by-count":29,"title":["Inhibition of K\n                    <sup>+<\/sup>\n                    secretion in the distal nephron in nephrotic syndrome: possible role of albuminuria"],"prefix":"10.1113","volume":"589","author":[{"given":"Marc","family":"Fila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Brideau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Morla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydie","family":"Cheval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Desch\u00eanes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Doucet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,7,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006050426"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1998.629bm.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00399.2005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1681\/ASN.V114604","article-title":"Collecting duct (Na+\/K+)\u2010ATPase activity is correlated with urinary sodium excretion in rat nephrotic syndromes","volume":"11","author":"Deschenes G","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V123598"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-007-0521-3"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.90475.2008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-89-21833"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00471.2004"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1152\/ajplegacy.1961.201.2.318","article-title":"Secretion of potassium and acidification in collecting ducts of mammalian kidney","volume":"201","author":"Hierholzer K","year":"1961","journal-title":"Am J Physiol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/362031a0"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110756"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00293.2007"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.70.113006.100651"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1271"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510609103"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609555104"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005040363"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2006.04.002"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1964.206.4.674"},{"key":"e_1_2_6_22_1","first-page":"255","article-title":"[Tubular origin of potassium excreted by the kidney; experimental study with radiopotassium K42 in rabbits] (in French)","volume":"14","author":"Morel F","year":"1956","journal-title":"Helv Physiol Pharmacol Acta"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.10.055"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.104.4.693"},{"key":"e_1_2_6_25_1","first-page":"887","article-title":"Albumin induces interleukin\u20106 release from primary human proximal tubule epithelial cells","volume":"21","author":"Pearson AL","year":"2008","journal-title":"J Nephrol"},{"key":"e_1_2_6_26_1","first-page":"29","article-title":"Pathophysiology of experimental nephrotic syndrome induced by puromycin aminonucleoside in rats. 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