{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:31:52Z","timestamp":1760783512608},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T00:00:00Z","timestamp":1337040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2012,5,15]]},"abstract":"<jats:p><jats:bold>Key points\u2002<\/jats:bold> <jats:list list-type=\"explicit-label\">\n<jats:list-item><jats:p>The cerebral ventricles of the vertebrate brain form a series of interconnected chambers through which cerebrospinal fluid flows serving an important role in brain homeostasis and development.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>We introduce the larval zebrafish brain as a model for studying the physiology of the cerebral ventricles.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The three dimensional form of the zebrafish ventricles was characterized by <jats:italic>in vivo<\/jats:italic> confocal microscopy and found to be similar to that of mammals.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>To follow the movement of molecules within ventricles we have a developed a technique using the uncaging of a fluorescent molecule.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Zebrafish larvae provide a tractable model for studying ventricles and the movement of chemicals across the blood\u2013brain barrier.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1113\/jphysiol.2011.225896","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T04:27:43Z","timestamp":1330403263000},"page":"2233-2240","source":"Crossref","is-referenced-by-count":18,"title":["A method for 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