{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:28:58Z","timestamp":1771622938587,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1969,11,1]],"date-time":"1969-11-01T00:00:00Z","timestamp":-5270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1969,11]]},"abstract":"<jats:p>1. The behaviour of membrane currents in a giant muscle fibre of a certain barnacle <jats:italic>Balanus nubilus<\/jats:italic>, Darwin, was studied by using voltage clamp technique after treating fibres with a Ca\u2010chelating internal solution.<\/jats:p><jats:p>2. Membrane currents can be classified into an early transient current and a late outward current.<\/jats:p><jats:p>3. The early transient current can be considered a sum of an inward and an outward component of different properties.<\/jats:p><jats:p>4. A conditioning depolarization suppresses the inward component but not the outward component.<\/jats:p><jats:p>5. Procaine suppresses the outward component and Co ions suppress the inward component.<\/jats:p><jats:p>6. Changes in the external Ca ion concentration alter the inward component but not the outward component.<\/jats:p><jats:p>7. The inward component is considered to be carried by Ca ions and the outward component mainly by K ions.<\/jats:p><jats:p>8. The outward component of the early current is similar to the current expected from the resting membrane conductance.<\/jats:p><jats:p>9. It is concluded that the early conductance increase of the barnacle muscle fibre membrane occurs only to Ca ions but not to K ions, although the membrane potential at the peak of spike is determined by both ions.<\/jats:p>","DOI":"10.1113\/jphysiol.1969.sp008955","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T12:05:55Z","timestamp":1418990755000},"page":"115-129","source":"Crossref","is-referenced-by-count":72,"title":["Calcium and potassium currents of the membrane of a barnacle muscle fibre in relation to the calcium spike"],"prefix":"10.1113","volume":"205","author":[{"given":"Susumu","family":"Hagiwara","sequence":"first","affiliation":[]},{"given":"Hideo","family":"Hayashi","sequence":"additional","affiliation":[]},{"given":"Kunitaro","family":"Takahashi","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[1969,11]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1969.sp008955","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1969.sp008955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T08:44:19Z","timestamp":1699433059000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1969.sp008955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,11]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1969,11]]}},"alternative-id":["10.1113\/jphysiol.1969.sp008955"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1969.sp008955","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,11]]}}}