{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:21:24Z","timestamp":1758396084683},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1976,2,1]],"date-time":"1976-02-01T00:00:00Z","timestamp":191980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1976,2]]},"abstract":"<jats:p>After confirming the region of the sino\u2010atrial (S\u2010A) node by its characteristic action potential, man\u2010made strands including the pacemaker region of the rabbit heart were prepared and simple cable theory analysis performed. The estimated gamma was 828 mum in Tyrode. 2. The single sucrose gap method was employed to conduct both the current\u2010clamp experiment and the voltage\u2010clamp experiment. In both methods outward\u2010going and inward\u2010going rectification were observed. 3. The existence of a positive after\u2010potential in the case of the current\u2010clamp experiment and of an outward current tail in the case of the voltage\u2010clamp experiment after cessation of cathodal pulses suggests that the outward\u2010going rectification is due to the increase of K conductance. 4. The slowly developed inward\u2010going rectification was always accompanied with a decrease of membrane resistance. It is unlikely that change in K conductance is solely responsible for this rectification. Discussion was made of the possibility that changes in both Na and Cl conductance together with K conductance might be involved.<\/jats:p>","DOI":"10.1113\/jphysiol.1976.sp011285","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T08:59:53Z","timestamp":1418979593000},"page":"379-397","source":"Crossref","is-referenced-by-count":59,"title":["Characteristics of the rectifying properties of the sino\u2010atrial node cell of the rabbit."],"prefix":"10.1113","volume":"255","author":[{"given":"I","family":"Seyama","sequence":"first","affiliation":[]}],"member":"311","published-online":{"date-parts":[[1976,2]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1976.sp011285","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1976.sp011285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T10:31:56Z","timestamp":1699180316000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1976.sp011285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,2]]}},"alternative-id":["10.1113\/jphysiol.1976.sp011285"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1976.sp011285","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,2]]}}}