{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T01:55:45Z","timestamp":1784253345118,"version":"3.55.0"},"reference-count":13,"publisher":"ASME International","issue":"4","content-domain":{"domain":["asmedigitalcollection.asme.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1997,11,1]]},"abstract":"<jats:p>A Monte Carlo model is described for modeling photo propagation in a scattering medium. The fraction of locally absorbed photons is proportional to the local rate of heat generation in laser-irradiated tissue and the associated distribution of light (fluence rate) is obtained by dividing the rate of heat generation by the local absorption coefficient. Examples of computed distributions of the rate of heat generation are presented for situations where light scattering in tissue is important. The method is applied to analyze treatment of Port Wine Stain and the selection of laser wave-lengths for cyclophotocoagulation.<\/jats:p>","DOI":"10.1115\/1.2798298","type":"journal-article","created":{"date-parts":[[2008,2,21]],"date-time":"2008-02-21T15:48:52Z","timestamp":1203608932000},"page":"489-495","update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":26,"title":["Monte Carlo Model for Determination of the Role of Heat Generation in Laser-Irradiated Tissue"],"prefix":"10.1115","volume":"119","author":[{"given":"A. J.","family":"Welch","sequence":"first","affiliation":[{"name":"Biomedical Engineering Program, The University of Texas at Austin, Austin, TX 78712"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. M.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Program, The University of Texas at Austin, Austin, TX 78712"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[1997,11,1]]},"reference":[{"key":"2019100409161069500_r1","doi-asserted-by":"crossref","unstructured":"Anderson\n              R. R.\n            , and ParrishJ. A., 1981, \u201cThe Optics of Human Skin,\u201d J. Invest. Dermatol., Vol. 77, pp. 13\u201319.","DOI":"10.1111\/1523-1747.ep12479191"},{"key":"2019100409161069500_r2","doi-asserted-by":"crossref","unstructured":"Boulnois\n              J.-L.\n            \n          , 1986, \u201cPhotophysical processes in recent medical laser developments: a review,\u201d Lasers Surg. Med., Vol. 1(1), pp. 47\u201366.","DOI":"10.1007\/BF02030737"},{"key":"2019100409161069500_r3","doi-asserted-by":"crossref","unstructured":"Flock\n              S. T.\n            , PattersonM. S., WilsonB. C., and WymanD. R., 1989, \u201cMonte Carlo modeling of light propagation in highly scattering tissues-I: Model predictions and comparison with diffusion theory,\u201d IEEE Trans. Biomed. Eng., Vol. 36(12), pp. 1162\u20131167.","DOI":"10.1109\/TBME.1989.1173624"},{"key":"2019100409161069500_r4","doi-asserted-by":"crossref","unstructured":"Ishimaru, A., 1978, Wave Propagation and Scattering in Random Media, Vol. 1, Academic Press, New York.","DOI":"10.1016\/B978-0-12-374701-3.50007-7"},{"key":"2019100409161069500_r5","doi-asserted-by":"crossref","unstructured":"Jacques\n              S. L.\n            , and McAuliffeD. J., 1991, \u201cThe Melanosome: Threshold Temperature for Explosive Vaporization and Internal Absorption Coefficient During Pulsed Laser Irradiation,\u201d Photochem Photobiol., Vol. 53, pp. 769\u2013775.","DOI":"10.1111\/j.1751-1097.1991.tb09891.x"},{"key":"2019100409161069500_r6","doi-asserted-by":"crossref","unstructured":"Keijzer\n              M.\n            , JacquesS. L., PrahlS. A., and WelchA. J., 1989, \u201cLight Distributions in Artery Tissue: Monte Carlo Distributions for Finite Laser Beams,\u201d Lasers Surg. Med., Vol. 9, pp. 148\u2013154.","DOI":"10.1002\/lsm.1900090210"},{"key":"2019100409161069500_r7","doi-asserted-by":"crossref","unstructured":"Lucassen\n              G. W.\n            , VerkruysseW., KeijzerM., and van GemertM. J. C., 1996, \u201cLight Distributions in a Port Wine Stain Model Containing Multiple Cylindrical and Curved Blood Vessels,\u201d Lasers Surg. Med., Vol. 18, pp. 345\u2013357.","DOI":"10.1002\/(SICI)1096-9101(1996)18:4<345::AID-LSM3>3.0.CO;2-S"},{"key":"2019100409161069500_r8","doi-asserted-by":"crossref","unstructured":"Nemati\n              B.\n            , RylanderH. G., WelchA. J., 1996, \u201cOptical Properties of Conjunctiva, Sclera, and Ciliary Body and Their Consequences for Transscleral Cyclophotocoagulation,\u201d Applied Optics, Vol. 35(19), pp. 3321\u20133327.","DOI":"10.1364\/AO.35.003321"},{"key":"2019100409161069500_r9","doi-asserted-by":"crossref","unstructured":"Tan\n              O. T.\n            , MorrisonP., and KurbanA. K., 1990, \u201c585 nm Treatment for Portwine Stains,\u201d Plast. Reconstr. Surg., Vol. 86, pp. 1112\u20131119.","DOI":"10.1097\/00006534-199012000-00011"},{"key":"2019100409161069500_r10","doi-asserted-by":"crossref","unstructured":"van Gemert, M. J. C., and Welch, A. J., 1991, \u201cCan Physical Modeling Lead to an Optimal Laser Treatment Strategy for Port Wine Stains?\u201d in: Laser Applications in Medicine and Biology, R. W. Waynant, ed., Plenum Press, New York, Vol. 5, pp. 189\u2013276.","DOI":"10.1007\/978-1-4899-1704-1_5"},{"key":"2019100409161069500_r11","unstructured":"Wang, L. H., and Jacques, S. L., 1992, \u201cMonte Carlo modeling of light transport in multi-layered tissues in standard C,\u201d University of Texas, M.D. Anderson Cancer Center."},{"key":"2019100409161069500_r12","unstructured":"Welch, A. J., and Gardner, C. M., in press, \u201cOptical and Thermal Response of Tissue to Laser Radiation,\u201d in: Lasers in Medicine, R. W. Waynant, ed., Plenum Press, New York."},{"key":"2019100409161069500_r13","doi-asserted-by":"crossref","unstructured":"Welch, A. J., and van Gemert, M. J. C., eds., 1995, Optical-Thermal Response of Laser-Irradiated Tissue, Plenum Press, New York.","DOI":"10.1007\/978-1-4757-6092-7"}],"container-title":["Journal of Biomechanical Engineering"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/asmedigitalcollection.asme.org\/biomechanical\/article-pdf\/119\/4\/489\/5766846\/489_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/asmedigitalcollection.asme.org\/biomechanical\/article-pdf\/119\/4\/489\/5766846\/489_1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T09:16:20Z","timestamp":1570180580000},"score":1,"resource":{"primary":{"URL":"https:\/\/asmedigitalcollection.asme.org\/biomechanical\/article\/119\/4\/489\/398187\/Monte-Carlo-Model-for-Determination-of-the-Role-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11,1]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,11,1]]}},"URL":"https:\/\/doi.org\/10.1115\/1.2798298","relation":{},"ISSN":["0148-0731","1528-8951"],"issn-type":[{"value":"0148-0731","type":"print"},{"value":"1528-8951","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,11,1]]}}}