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We believe that there is experimental support for an additional pathway, where an increase in the amount of osteoclasts, and thus osteolysis, is caused by the time history of fluid flow velocity, fluid pressure, or other parameters related to fluid flow at the bone\/soft tissue interface of the porosities in the bone.<\/jats:p>","DOI":"10.1115\/1.3194756","type":"journal-article","created":{"date-parts":[[2009,8,28]],"date-time":"2009-08-28T22:37:09Z","timestamp":1251499029000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":28,"title":["Bone Resorption Induced by Fluid Flow"],"prefix":"10.1115","volume":"131","author":[{"given":"Lars","family":"Johansson","sequence":"first","affiliation":[{"name":"Department of Management and Engineering, Link\u00f6ping University, SE-581 83 Link\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Edlund","sequence":"additional","affiliation":[{"name":"Department of Management and Engineering, Link\u00f6ping University, SE-581 83 Link\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Fahlgren","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Link\u00f6ping University, SE-581 83 Link\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Aspenberg","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Link\u00f6ping University, SE-581 83 Link\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"33","published-online":{"date-parts":[[2009,8,7]]},"reference":[{"key":"2019100512243514600_c1","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/0021-9290(87)90058-3","article-title":"Trabecular Bone Density and Loading History: Regulation of Connectivity Tissue Biology by Mechanical Energy","volume":"20","author":"Carter","journal-title":"J. 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