{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:43:43Z","timestamp":1790073823061,"version":"4.0.1"},"reference-count":45,"publisher":"ASME International","issue":"11","content-domain":{"domain":["asmedigitalcollection.asme.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,11,1]]},"abstract":"<jats:p>Periprosthetic osteolysis in the retroacetabular region with cancellous bone loss is a recognized phenomenon in the long-term follow-up of total hip replacement. The effects on load transfer in the presence of defects are less well known. A validated, patient-specific, 3D finite element (FE) model of the pelvis was used to assess changes in load transfer associated with periprosthetic osteolysis adjacent to a cementless total hip arthroplasty (THA) component. The presence of a cancellous defect significantly increased (p\u2009&lt;\u20090.05) von Mises stress in the cortical bone of the pelvis during walking and a fall onto the side. At loads consistent with single leg stance, this was still less than the predicted yield stress for cortical bone. During higher loads associated with a fall onto the side, highest stress concentrations occurred in the superior and inferior pubic rami and in the anterior column of the acetabulum with larger cancellous defects.<\/jats:p>","DOI":"10.1115\/1.4028522","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T22:31:18Z","timestamp":1410301878000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":6,"title":["Altered Load Transfer in the Pelvis in the Presence of Periprosthetic Osteolysis"],"prefix":"10.1115","volume":"136","author":[{"given":"Jacob T.","family":"Munro","sequence":"first","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland, Auckland 1142, New Zealand e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin W.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland, Auckland 1142, New Zealand e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"Millar","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland, Auckland 1142, New Zealand e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron G.","family":"Walker","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland, Auckland 1142, New Zealand e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald W.","family":"Howie","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, University of Adelaide, Adelaide 1142, South Australia e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vickie B.","family":"Shim","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland, Auckland 1142, New Zealand e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[2014,9,24]]},"reference":[{"key":"2019100601452424500_B1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.blo.0000238813.95035.1b","article-title":"The Cellular and Molecular Biology of Periprosthetic Osteolysis","volume":"454","year":"2007","journal-title":"Clin. 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