{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:40:31Z","timestamp":1790790031612,"version":"4.1.0"},"reference-count":72,"publisher":"ASME International","issue":"6","license":[{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.asme.org\/publications-submissions\/publishing-information\/legal-policies"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL121293"],"award-info":[{"award-number":["R01HL121293"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["asmedigitalcollection.asme.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In this work, we provide a quantitative assessment of the biomechanical and geometric features that characterize abdominal aortic aneurysm (AAA) models generated from 19 Asian and 19 Caucasian diameter-matched AAA patients. 3D patient-specific finite element models were generated and used to compute peak wall stress (PWS), 99th percentile wall stress (99th WS), and spatially averaged wall stress (AWS) for each AAA. In addition, 51 global geometric indices were calculated, which quantify the wall thickness, shape, and curvature of each AAA. The indices were correlated with 99th WS (the only biomechanical metric that exhibited significant association with geometric indices) using Spearman's correlation and subsequently with multivariate linear regression using backward elimination. For the Asian AAA group, 99th WS was highly correlated (R2\u2009=\u20090.77) with three geometric indices, namely tortuosity, intraluminal thrombus volume, and area-averaged Gaussian curvature. Similarly, 99th WS in the Caucasian AAA group was highly correlated (R2\u2009=\u20090.87) with six geometric indices, namely maximum AAA diameter, distal neck diameter, diameter\u2013height ratio, minimum wall thickness variance, mode of the wall thickness variance, and area-averaged Gaussian curvature. Significant differences were found between the two groups for ten geometric indices; however, no differences were found for any of their respective biomechanical attributes. Assuming maximum AAA diameter as the most predictive metric for wall stress was found to be imprecise: 24% and 28% accuracy for the Asian and Caucasian groups, respectively. This investigation reveals that geometric indices other than maximum AAA diameter can serve as predictors of wall stress, and potentially for assessment of aneurysm rupture risk, in the Asian and Caucasian AAA populations.<\/jats:p>","DOI":"10.1115\/1.4045268","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T11:02:35Z","timestamp":1571655755000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":5,"title":["A Comparative Study of Biomechanical and Geometrical Attributes of Abdominal Aortic Aneurysms in the Asian and Caucasian Populations"],"prefix":"10.1115","volume":"142","author":[{"given":"Tejas","family":"Canchi","sequence":"first","affiliation":[{"name":"School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sourav S.","family":"Patnaik","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong N.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Texas at San Antonio, San Antonio, TX 78249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Y. K.","family":"Ng","sequence":"additional","affiliation":[{"name":"School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sriram","family":"Narayanan","sequence":"additional","affiliation":[{"name":"The Harley Street Heart and Vascular Centre, Gleneagles Hospital, Singapore 258500"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish C.","family":"Muluk","sequence":"additional","affiliation":[{"name":"Department of Thoracic & Cardiovascular Surgery, Allegheny Health Network, Pittsburgh, PA 15212"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"De Oliveira","sequence":"additional","affiliation":[{"name":"Department of Management and Statistics, University of Texas at San Antonio, San Antonio, TX 78249"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ender A.","family":"Finol","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, EB 3.04.08, San Antonio, TX 78249"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[2020,1,23]]},"reference":[{"issue":"3","key":"2020012308192073200_bib1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1046\/j.1365-2168.2001.01709.x","article-title":"Epidemiology of Abdominal Aortic Aneurysms in the Asian Community","volume":"88","year":"2001","journal-title":"Br. 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