{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:35:10Z","timestamp":1783420510455,"version":"3.54.6"},"reference-count":38,"publisher":"ASME International","issue":"6","license":[{"start":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T00:00:00Z","timestamp":1585267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.asme.org\/publications-submissions\/publishing-information\/legal-policies"}],"funder":[{"name":"Tennessee Higher Education Commission","award":["R041302175"],"award-info":[{"award-number":["R041302175"]}]}],"content-domain":{"domain":["asmedigitalcollection.asme.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The objective of this study is to explore the complexity of airflow through the human respiratory tract by carrying out computational fluid dynamics simulation. In order to capture the detailed physics of the flow in this complex system, large eddy simulation (LES) is performed. The crucial step in this analysis is to investigate the impact of breathing transience on the flow field. In this connection, simulations are carried out for transient breathing in addition to peak inspiration and expiration. To enable a fair comparison, the flowrates for constant inspiration\/expiration are selected to be identical to the peak flowrates during the transient breathing. Physiologically appropriate regional ventilation for two different flowrates is induced. The velocity field and turbulent flow features are discussed for both flowrates. The airflow through the larynx is observed to be significantly complex with high turbulence level, recirculation, and secondary flow while the level of turbulence decreases through the higher bifurcations.<\/jats:p>","DOI":"10.1115\/1.4046005","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T09:19:57Z","timestamp":1579511997000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":12,"title":["Numerical Simulation of Tidal Breathing Through the Human Respiratory Tract"],"prefix":"10.1115","volume":"142","author":[{"given":"Jamasp","family":"Azarnoosh","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, The University of Tennessee at Chattanooga, Chattanooga, TN 37403"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kidambi","family":"Sreenivas","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, The University of Tennessee at Chattanooga, Chattanooga, TN 37403"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdollah","family":"Arabshahi","sequence":"first","affiliation":[{"name":"SimCenter - Center of Excellence in Applied Computational Science and Engineering, The University of Tennessee at Chattanooga, Chattanooga, TN 37403"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[2020,3,27]]},"reference":[{"key":"2020032712191356800_bib1","article-title":"Action Plan of the Global Alliance Against Chronic Respiratory Diseases","year":"2008"},{"issue":"17","key":"2020032712191356800_bib2","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The Occurrence of Sleep-Disordered Breathing Among Middle-Aged Adults","volume":"328","year":"1993","journal-title":"New Engl. 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