{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:48:44Z","timestamp":1791560924693,"version":"4.3.4"},"reference-count":58,"publisher":"ASME International","issue":"11","license":[{"start":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T00:00:00Z","timestamp":1599177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.asme.org\/publications-submissions\/publishing-information\/legal-policies"}],"content-domain":{"domain":["asmedigitalcollection.asme.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Accurate failure criteria play a fundamental role in biomechanical analyses of aortic wall rupture and dissection. Experimental investigations have demonstrated a significant difference of aortic wall strengths in the circumferential and axial directions. Therefore, the isotropic von Mises stress and maximum principal stress, commonly used in computational analysis of the aortic wall, are inadequate for modeling of anisotropic failure properties. In this study, we propose a novel stress-based anisotropic failure criterion with dispersed fiber orientations. In the new failure criterion, the overall failure metric is computed by using angular integration (AI) of failure metrics in all directions. Affine rotations of fiber orientations due to finite deformation are taken into account in an anisotropic hyperelastic constitutive model. To examine fitting capability of the failure criterion, a set of off-axis uniaxial tension tests were performed on aortic tissues of four porcine individuals and 18 human ascending thoracic aortic aneurysm (ATAA) patients. The dispersed fiber failure criterion demonstrates a good fitting capability with the off-axis testing data. Under simulated biaxial stress conditions, the dispersed fiber failure criterion predicts a smaller failure envelope comparing to those predicted by the traditional anisotropic criteria without fiber dispersion, which highlights the potentially important role of fiber dispersion in the failure of the aortic wall. Our results suggest that the deformation-dependent fiber orientations need to be considered when wall strength determined from uniaxial tests are used for in vivo biomechanical analysis. More investigations are needed to determine biaxial failure properties of the aortic wall.<\/jats:p>","DOI":"10.1115\/1.4048029","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T14:07:29Z","timestamp":1596809249000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":28,"title":["A Novel Anisotropic Failure Criterion With Dispersed Fiber Orientations for Aortic Tissues"],"prefix":"10.1115","volume":"142","author":[{"given":"Minliang","family":"Liu","sequence":"first","affiliation":[{"name":"Tissue Mechanics Laboratory, The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30313"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Dong","sequence":"additional","affiliation":[{"name":"Tissue Mechanics Laboratory, The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30313"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Lou","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, GA 30332"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Iannucci","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, GA 30332"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward P.","family":"Chen","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, GA 30332"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley G.","family":"Leshnower","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Atlanta, GA 30332"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"Tissue Mechanics Laboratory, The Wallace H. 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