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Standardized laboratory impact testing, such as the yearly National Football League (NFL) helmet test, is used to rank the protective performance of football helmets, motivating new technologies to improve the safety of helmets relative to existing equipment. In this work, we hypothesized that a helmet which transmits a nearly constant minimum force will result in a reduced risk of mTBI. To evaluate the plausibility of this hypothesis, we first show that the optimal force transmitted to the head, in a reduced order model of the brain, is in fact a constant force profile. To simulate the effects of a constant force within a helmet, we conceptualize a fluid-based shock absorber system for use within a football helmet. We integrate this system within a computational helmet model and simulate its performance on the standard NFL helmet test impact conditions. The simulated helmet is compared with other helmet designs with different technologies. Computer simulations of head impacts with liquid shock absorption predict that, at the highest impact speed (9.3\u2009m\/s), the average brain tissue strain is reduced by 27.6%\u2009\u00b1\u20099.3 compared to existing helmet padding when tested on the NFL helmet protocol. This simulation-based study puts forth a target benchmark for the future design of physical manifestations of this technology.<\/jats:p>","DOI":"10.1115\/1.4049155","type":"journal-article","created":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T03:53:37Z","timestamp":1605758017000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":20,"title":["A Computational Study of Liquid Shock Absorption for Prevention of Traumatic Brain Injury"],"prefix":"10.1115","volume":"143","author":[{"given":"Hossein","family":"Vahid Alizadeh","sequence":"first","affiliation":[{"name":"Bioengineering Department, Stanford University, Stanford, CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Fanton","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Stanford University, Stanford, CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"August G.","family":"Domel","sequence":"additional","affiliation":[{"name":"Bioengineering Department, Stanford University, Stanford, CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University, Stanford, CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Benjamin","family":"Camarillo","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Stanford University, Stanford, CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"issue":"8","key":"2021020106591064800_bib1","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1007\/s10439-014-1212-4","article-title":"Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury","volume":"43","year":"2015","journal-title":"Ann. 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