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However, the biomechanical mechanism between the OPLL type and the clinical characteristics of myelopathy remains unclear. The aim of this study was to evaluate the effect of different types of OPLL on the dynamic biomechanical response of the spinal cord. A three-dimensional finite element model of the fluid\u2013structure interaction of the cervical spine with spinal cord was established and validated. The spinal cord stress and strain, cervical range of motion (ROM) in different types of OPLL models were predicted during dynamic flexion and extension activity. Different types of OPLL models showed varying degrees of increase in stress and strain under the process of flexion and extension, and there was a surge toward the end of extension. Larger spinal cord stress was observed in segmental OPLL. For continuous and mixed types of OPLL, the adjacent segments of OPLL showed a dramatic increase in ROM, while the ROM of affected segments was limited. As a dynamic factor, flexion and extension of the cervical spine play an amplifying role in OPLL-related myelopathy, while appropriate spine motion is safe and permitted. Segmental OPLL patients are more concerned about the spinal cord injury induced by large stress, and patients with continuous OPLL should be noted to progressive injuries of adjacent level.<\/jats:p>","DOI":"10.1115\/1.4063194","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T12:13:31Z","timestamp":1692015211000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Different Types of Ossification of the Posterior Longitudinal Ligament on the Dynamic Biomechanical Response of the Spinal Cord: A Finite Element Analysis"],"prefix":"10.1115","volume":"145","author":[{"given":"Liang-dong","family":"Zheng","sequence":"first","affiliation":[{"name":"Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"},{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Tongji Hospital, School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-ting","family":"Cao","sequence":"additional","affiliation":[{"name":"Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"},{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Tongji Hospital, School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-ting","family":"Yang","sequence":"additional","affiliation":[{"name":"Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"},{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Tongji Hospital, School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-lei","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"},{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Tongji Hospital, School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-zi","family":"Zeng","sequence":"additional","affiliation":[{"name":"Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University , Shanghai 200092, China; , 389 Xincun Road, Shanghai 200065, China"},{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Tongji Hospital, School of Medicine, Tongji University , Shanghai 200092, China; 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