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In the experiment, a rabbit larynx was used to simulate type 1 thyroplasty, where one side of the vocal fold was medialized with a trans-muscular suture while the other side was medialized with a silastic implant. Vocal fold vibration was then achieved by flowing air through the larynx and was filmed with a high-speed camera. The three-dimensional computational model was built upon the pre-operative scan of the laryngeal anatomy. This subject-specific model was used to simulate the vocal fold medialization and then the fluid-structure interaction (FSI) of the vocal fold. Model validation was done by comparing the vocal fold displacement with postoperative scan (for medialization), and by comparing the vibratory characteristics with the high-speed images (for vibration). These comparisons showed the computational model successfully captured the effect of the implant and thus has the potential for presurgical planning.<\/jats:p>","DOI":"10.1115\/1.4064662","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:58:42Z","timestamp":1707213522000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":4,"title":["An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty"],"prefix":"10.1115","volume":"146","author":[{"given":"Amit","family":"Avhad","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, Vanderbilt University , Nashville, TN 37221"},{"id":[{"id":"https:\/\/ror.org\/02vm5rt34","id-type":"ROR","asserted-by":"publisher"}],"name":"Vanderbilt University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azure","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Communication Science and Disorders, University of Pittsburgh , Pittsburgh, PA 15260"},{"id":[{"id":"https:\/\/ror.org\/01an3r305","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pittsburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea","family":"Sayce","sequence":"additional","affiliation":[{"name":"Department of Communication Science and Disorders, University of Pittsburgh , Pittsburgh, PA 15260"},{"id":[{"id":"https:\/\/ror.org\/01an3r305","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pittsburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Li","sequence":"additional","affiliation":[{"name":"Mechatronics Engineering Department, Morgan State University , Baltimore, MD 21251"},{"id":[{"id":"https:\/\/ror.org\/017d8gk22","id-type":"ROR","asserted-by":"publisher"}],"name":"Morgan State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Doisy College of Health Sciences, Saint Louis University , Saint Louis, MO 63103"},{"id":[{"id":"https:\/\/ror.org\/01p7jjy08","id-type":"ROR","asserted-by":"publisher"}],"name":"Saint Louis University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Doyle","sequence":"additional","affiliation":[{"name":"School of Aeronautics and Astronautics, Purdue University , West Lafayette, IN 47907"},{"id":[{"id":"https:\/\/ror.org\/02dqehb95","id-type":"ROR","asserted-by":"publisher"}],"name":"Purdue University West Lafayette"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoxiang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Vanderbilt University , Nashville, TN 37235-1592"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"33","published-online":{"date-parts":[[2024,2,23]]},"reference":[{"key":"2024022314195994000_bib1","article-title":"Anatomy, Head and Neck, Larynx Vocal Cords","volume-title":"StatPearls [Internet]","year":"2022"},{"issue":"2","key":"2024022314195994000_bib2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00005537-200002010-00010","article-title":"Redefining the Survival of the Fittest: Communication Disorders in the 21st Century","volume":"110","year":"2000","journal-title":"Laryngoscope"},{"issue":"2","key":"2024022314195994000_bib3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1044\/2020_JSLHR-20-00344","article-title":"Medialization Laryngoplasty: A Review for Speech-Language Pathologists","volume":"64","year":"2021","journal-title":"J. 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