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Active-duty military populations are generally stronger than the civilian population; therefore, musculoskeletal models with military-specific muscle strengths are needed, especially if they are used for injury prediction. The purpose was to evaluate the effect of muscle strength personalization on muscle excitation prediction accuracy from movement simulations of musculoskeletal models. Maximum voluntary isometric contractions (MVICs) of lumbar, hip, knee, and ankle muscles were measured with an instrumented dynamometer for 16 active-duty participants. These measurements were used to personalize muscle maximum isometric force from a generic musculoskeletal model to create strength-scaled models. Participants walked under two conditions: (1) no-pack (body armor and helmet) and (2) pack with 46\u2009kg total load (body armor, helmet, and posteriorly loaded backpack). Full-body kinematics, ground reaction forces (GRFs), and right-side electromyography (EMG) of 11 lower-limb and torso muscles were collected. Muscle-driven simulations were produced using both generic and strength-scaled models for each condition. Simulation accuracy was determined by comparing measured electromyography signals to simulated muscle excitations using a root-mean-square difference (RMSD). Personalized muscle strength scaling improved overall muscle excitation predictions in walking simulations of military service members carrying heavy backpacks by 19% (p\u2009&amp;lt;\u2009.001). Improved model accuracy enables better predictions of internal joint mechanics, which are important for understanding injury risk and evaluating injury prevention strategies.<\/jats:p>","DOI":"10.1115\/1.4071130","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:40:58Z","timestamp":1771335658000},"update-policy":"https:\/\/doi.org\/10.1115\/crossmarkpolicy-asme","source":"Crossref","is-referenced-by-count":0,"title":["Personalized Muscle Strength Improves Accuracy of Military Load Carriage Simulations"],"prefix":"10.1115","volume":"148","author":[{"given":"Anna C.","family":"Corman","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, Colorado School of Mines , 1500 Illinois Street, Golden, CO 80401"},{"id":[{"id":"https:\/\/ror.org\/04raf6v53","id-type":"ROR","asserted-by":"publisher"}],"name":"Colorado School of Mines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7619-5156","authenticated-orcid":false,"given":"Jordan T.","family":"Sturdy","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Colorado School of Mines , 1500 Illinois Street, Golden, CO 80401"},{"id":[{"id":"https:\/\/ror.org\/04raf6v53","id-type":"ROR","asserted-by":"publisher"}],"name":"Colorado School of Mines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedaya N.","family":"Rizeq","sequence":"additional","affiliation":[{"name":"Military and Veterans Health Solutions, Leidos, Inc. , San Diego, CA 92106 ; , 140 Sylvester Road, San Diego, CA 92106"},{"name":"Warfighter Performance Department, Naval Health Research Center , San Diego, CA 92106 ; , 140 Sylvester Road, San Diego, CA 92106"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlie J.","family":"Daquino","sequence":"additional","affiliation":[{"name":"Military and Veterans Health Solutions, Leidos, Inc. , San Diego, CA 92106 ; , 140 Sylvester Road, San Diego, CA 92106"},{"name":"Warfighter Performance Department, Naval Health Research Center , San Diego, CA 92106 ; , 140 Sylvester Road, San Diego, CA 92106"},{"id":[{"id":"https:\/\/ror.org\/01hzj5y23","id-type":"ROR","asserted-by":"publisher"}],"name":"Naval Health Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler T.","family":"Whittier","sequence":"additional","affiliation":[{"name":"Department of Food Systems, Nutrition and Kinesiology, Montana State University , 950 W. 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