{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T22:29:24Z","timestamp":1785364164833,"version":"3.55.0"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Pentalogy of Cantrell (POC) is a rare condition characterized by complete or partial expression of 5 types of congenital\u00a0birth defects originating in (1) the lower sternum, (2) the anterior diaphragm, (3) the diaphragmatic pericardium, (4) the\u00a0midline\/ventral supraumbilical abdominal wall region, and (5) the heart. POC can be diagnosed antenatally by means of ultrasonography\u00a0(US), the task being difficult if defects are minor. Advances in the field of US and the introduction of the first\u00a0morphology trimester as state-of-the-art pregnancy monitoring, facilitate the early diagnosis of this condition. We performed a\u00a0systematic review on 67 reported cases of POC diagnosed in the first trimester of pregnancy (published from January 1980 to\u00a0July 2019). The aim of our systematic review was twofold: to assess the main US findings in the first trimester of pregnancy\u00a0and to increase awareness of early diagnostic possibilities. Our study showed that POC can be diagnosed in the first trimesterof pregnancy based on key US findings such as the association between omphalocele and ectopia cordis. When these two\u00a0anomalies are present, increased nuchal translucency can also be considered a marker of POC in the first trimester.<\/jats:p>","DOI":"10.11152\/mu-2316","type":"journal-article","created":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T20:11:36Z","timestamp":1580415096000},"page":"189","source":"Crossref","is-referenced-by-count":9,"title":["Cantrell syndrome in the first trimester of pregnancy: imagistic findings and literature review"],"prefix":"10.11152","volume":"22","author":[{"given":"Mihaela","family":"Grigore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romeo","family":"Micu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Matasariu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odetta","family":"Duma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca Lucia","family":"Chicea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu","family":"Chicea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4840","published-online":{"date-parts":[[2020,5,11]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/2316\/1474","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/2316\/1474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T19:02:01Z","timestamp":1589223721000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/2316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,11]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,5,11]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-2316","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5,11]]}}}