{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T05:07:15Z","timestamp":1745644035097},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aim: To explore the performance of single or combined ultrasound (US) in diagnosing malignant breast lesions, and then compare the results with a magnetic resonance imaging (MRI) aspect.Material and methods: Patients\u2019 demographics, tumor markers, and imaging examination were collected. Diagnostic models based on B-mode, color Doppler ultrasounds (CDU), strain elastography (SE), MRI, B-mode US + CDU, B-mode US + SE, and B-mode US + CDU + SE were developed using logistic regression analysis. The performance was assessed using the area under the curve (AUC) with 95% confidence intervals (CIs). Performance of MRI and B-mode US + CDU was compared using DeLong analysis.Results: For single imaging modality, MRI showed the best performance, with AUC of 0.938 (95%CI: 0.888-0.988). For combined US modalities, combination of B-mode US and CDU had the best performance, with AUC of 0.948 (95%CI: 0.877-1.000). There was no significant difference in the diagnostic performance between the combination of B-mode US and CDU and MRI (p&gt;0.05).Conclusions: Our study found the performance of B-mode + CDU was comparable to MRI. Our findings suggested that the combination of B-mode US and CDU was recommended to diagnose malignant breast lesions in order to save time and expense and provide guidance to make decisions for a biopsy<\/jats:p>","DOI":"10.11152\/mu-4335","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T05:47:41Z","timestamp":1707803261000},"page":"160","source":"Crossref","is-referenced-by-count":1,"title":["Comparison between combined ultrasounds and magnetic resonance imaging in the differentiation of benign and malignant breast lesions: a cross-sectional study"],"prefix":"10.11152","volume":"26","author":[{"given":"Chaoxi","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dehui","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4840","published-online":{"date-parts":[[2024,6,21]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4335\/2313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4335\/2313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T13:56:56Z","timestamp":1718978216000},"score":1,"resource":{"primary":{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/4335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,21]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,6,21]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-4335","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,21]]}}}