{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T09:22:07Z","timestamp":1787995327164,"version":"build-2784847793"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aims: To investigate the multimodal ultrasonography (US) features of extramedullary plasmacytomas (EMPs) in patients\u00a0with multiple myeloma (MM).Material and methods: Nine patients with MM who were diagnosed EMPs and underwent\u00a0multimodal ultrasonography were enrolled in this study. Clinical information and multimodal US results were retrospectively\u00a0analyzed. The multimodal US with a standardized sonographic protocol including US, color Doppler flow imaging (CDFI),\u00a0microvascular US, ultrasound elastography (UE) and contrast-enhanced ultrasound (CEUS) was performed on the enrolled\u00a0patients.Results: This study included both males (4 of 9) and females (5 of 9), with ages ranging from 48 to 72 years. The\u00a0nine lesions were located in the skin\/muscle (7 of 9) and pleura (2 of 9). On US images, all lesions showed inhomogeneous\u00a0solid hypoechogenicity without calcification. Vascularity was abundant (hypervascularization). CEUS images confirmed this\u00a0vascular pattern (9 of 9) and presented hyperenhancement with enlarged range. On elastographic images, the lesions presented\u00a0with high elastic score (3-4).Conclusions: An inhomogeneous hypoechoic soft tissue or visceral mass occurring in MM with\u00a0increased vascularity, low elasticity, and hyperenhancement along with enlarged range can indicate the diagnosis of EMP on\u00a0multimodal US images.<\/jats:p>","DOI":"10.11152\/mu-4503","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T09:44:59Z","timestamp":1744105499000},"page":"276","source":"Crossref","is-referenced-by-count":2,"title":["Multimodal ultrasonography features of the extramedullary plasmacytomas in multiple myeloma: a retrospective case series study"],"prefix":"10.11152","volume":"27","author":[{"given":"Jingyi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengxu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Hang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4840","published-online":{"date-parts":[[2025,9,17]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4503\/2511","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4503\/2511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T18:37:59Z","timestamp":1758134279000},"score":1,"resource":{"primary":{"URL":"https:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/4503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,17]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9,17]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-4503","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,17]]}}}