{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:48:39Z","timestamp":1782463719922,"version":"3.54.5"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aim: Presarcopenia represents the earliest stage of sarcopenia. While muscle ultrasound (US) and shear wave elastography\u00a0(SWE) offer promise as a non-invasive tool, its role in detecting early muscle loss remains underexplored, especially\u00a0in the upper limb. Therefore, the aim of this study was to characterize the flexor digitorum profundus (FDP) muscle in older\u00a0adults with presarcopenia versus normal muscle mass, and to assess the diagnostic potential of grayscale echogenicity and\u00a0SWE.Material and methods: This cross-sectional study included 50 age- and sex-matched participants classified as presarcopenic\u00a0(n=25) or normal muscle mass (n=25) based on dual-energy x-ray absorptiometry (DXA)-derived appendicular\u00a0skeletal muscle mass index (ASMI). All underwent clinical evaluation and ultrasound assessment of the FDP. US parameters\u00a0included cross-sectional area (CSA), muscle thickness (MT), pennation angle (PA), echogenicity, and SWE in relaxation and\u00a0contraction. Logistic regression and ROC analysis were applied.Results: Presarcopenic participants had significantly lower\u00a0CSA (p=0.001) and higher grayscale echogenicity (p&lt;0.001). MT and PA did not differ significantly. Echogenicity showed\u00a0negative correlations with CSA, DXA measurements, and forearm circumference (FC). Grayscale cut-off values were proposed\u00a0to differentiate visual echogenicity grades. Although SWE values were not significantly different in univariate analysis,\u00a0SWE in relaxation emerged as an independent predictor in the regression model.Conclusions: FDP grayscale echogenicity is\u00a0a strong marker of early muscle decline. SWE in relaxation independently predicted presarcopenia, supporting its role in early\u00a0diagnostic frameworks. Larger studies are warranted.\u00a0<\/jats:p>","DOI":"10.11152\/mu-4550","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:34:32Z","timestamp":1761554072000},"page":"162","source":"Crossref","is-referenced-by-count":0,"title":["Flexor digitorum profundus evaluation in normal muscle mass subjects and presarcopenic patients \u2013 a sonoelastographic cross-sectional study"],"prefix":"10.11152","volume":"28","author":[{"given":"Roxana Ioana","family":"Gutiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Ana","family":"Bilous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia","family":"Cozma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana","family":"Serban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Badarinza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fodor","family":"Daniela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4840","published-online":{"date-parts":[[2026,6,26]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4550\/2705","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4550\/2705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:19:54Z","timestamp":1782461994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/4550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,26]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6,26]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-4550","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,26]]}}}