{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:10:05Z","timestamp":1790244605705,"version":"4.1.0"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aim: Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) who present with symptom exacerbation [defined by a high IBS-Symptom Severity Scale (IBS-SSS)] may have increased fecal calprotectin (FC). Intestinal ultrasound (IUS) is used to measure bowel wall thickness (BWT). The aim of our study was to measure BWT in IBS-D patients, ulcerative colitis (UC) and healthy controls (HC), and compare BWT, IBS-SSS score, and FC level. Material and method: Patients with IBS-D and symptom exacerbation (n=100), active UC (n=25), and HC (n=30) were included. FC was measured in all groups. IBS-D patients with an IBS-SSS score &gt;75 and FC level &gt;50 \u00b5g\/g underwent IUS and colonoscopy. Results: Patients with IBS-D had a (mean\u00b1SEM) IBS-SSS score of 268\u00b111, FC level of 260\u00b146 \u00b5g\/g, and a normal colonoscopy. IUS showed a significant difference (p&lt;0.0001) between sigmoid BWT for IBS-D (3.16\u00b10.09 mm) and HC (1.6\u00b10.12 mm). Color Doppler signals were also absent. A significant correlation between sigmoid BWT and FC level (r=0.48, p=0.0012) was found in patients with IBS-D. Conclusion: Compared to HC, sigmoid BWT was significantly increased in IBS-D patients with symptom exacerbation. Sigmoid BWT correlates significantly with FC levels during IBS-D symptom exacerbation.<\/jats:p>","DOI":"10.11152\/mu-4592","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T08:42:26Z","timestamp":1772440946000},"page":"263","source":"Crossref","is-referenced-by-count":0,"title":["Sigmoid wall thickness correlates with fecal calprotectin during irritable bowel syndrome exacerbation"],"prefix":"10.11152","volume":"28","author":[{"given":"Tarek","family":"Mazzawi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Haj Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Nylund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odd Helge","family":"Gilja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4840","published-online":{"date-parts":[[2026,9,23]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4592\/2748","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/4592\/2748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:34:35Z","timestamp":1790242475000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/4592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,23]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-4592","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,23]]}}}