{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T02:28:37Z","timestamp":1654655317244},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Hyperimmunoglobulin D syndrome due to mevalonate kinase deficiency is a rare autoinflammatory disease with digestive\u00a0tract involvement. We report an 11-year female child who has presented since the age of 1 year, bouts of fever, rash, joint\u00a0swelling, pulmonary consolidation, lymph node involvement and hepatosplenomegaly. Hyperimmunglobulin D and increased\u00a0urinary mevalonic acid were detected. The ultrasonographic features of hepatosplenomegaly ranged from increment in size to\u00a0pseudotumoral involvement, with hypoechogenic masses without apparent wall. Abdominal CT during a disease flare showed\u00a0hypodense, hypoenhancing nodular lesions, suggesting metastases. Nevertheless, a thorough search for malignancy was negative\u00a0and the masses disappeared after the flare. Mevalonate kinase deficiency may add to the causes of hepatosplenic and\u00a0pulmonary inflammatory pseudotumors.<\/jats:p>","DOI":"10.11152\/mu-889","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T09:29:32Z","timestamp":1488533372000},"page":"224","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasonographic findings in hyperimmunoglobulin D syndrome: a case report"],"prefix":"10.11152","volume":"19","author":[{"given":"Laura Otilia","family":"Damian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otilia","family":"Fufezan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Farc\u0103u","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"T\u0103tar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u0103lin","family":"Laz\u0103r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorin-Ioan","family":"Farc\u0103u","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4840","published-online":{"date-parts":[[2017,4,22]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/889\/957","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/889\/957","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,4,22]],"date-time":"2017-04-22T16:33:28Z","timestamp":1492878808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,22]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,4,22]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-889","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4,22]]}}}