{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T10:50:44Z","timestamp":1789210244534,"version":"build-2803163510"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aims: Maternal red blood cell alloimmunization is an important cause of fetal morbidity and mortality in the perinatal\u00a0period, despite well-organized prophylaxis programs. The objective of the study was to evaluate placental elasticity by using\u00a0Acoustic Radiation Force Impulse (ARFI) in Rhesus (Rh) alloimmunized pregnant women with hydropic and nonhydropic\u00a0fetuses and to compare those with healthy pregnant women. Material and methods: This case-control and descriptive study\u00a0comprised twenty-eight healthy pregnant women, 14 Rh alloimmunized pregnant women with nonhydropic fetuses, and 16 Rh\u00a0alloimmunized pregnant women with hydropic fetuses in the third trimester of pregnancy. Placental elasticity measurements\u00a0were performed by ARFI elastosonography at the day of delivery. The maternal characteristics and neonatal outcomes of the\u00a0patients were also noted. Results: The highest mean placental ARFI scores were observed in Rh alloimmunized pregnant\u00a0women with hydropic fetuses (1.13 m\/s) (p=0.001). Healthy controls and Rh alloimmunized pregnant women with nonhydropic\u00a0fetuses had similar mean placenta ARFI scores (0.84 m\/s, 0.88 m\/s, respectively) (p&lt;0.05). Conclusions: Based on\u00a0the present findings, the placenta becomes stiffer in Rh alloimmunized pregnancies complicated with hydrops fetalis. The\u00a0increased placental ARFI scores may be a supplemental marker for adverse pregnancy outcomes, additional to Doppler evaluation\u00a0of middle cerebral artery. This data should be confirmed with a large sample size and prospective studies by using serial\u00a0measurements of ARFI elastosonography in maternal red blood cell alloimmunization.<\/jats:p>","DOI":"10.11152\/mu-924","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T13:13:44Z","timestamp":1482153224000},"page":"73","source":"Crossref","is-referenced-by-count":8,"title":["Acoustic radiation force impulse elastosonography of placenta in maternal red blood cell alloimmunization: a preliminary and descriptive study"],"prefix":"10.11152","volume":"19","author":[{"given":"Orkun","family":"Cetin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erbil","family":"Karaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harun","family":"Arslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Akbudak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recep","family":"Y\u0131ld\u0131zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Kolusar\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4840","published-online":{"date-parts":[[2017,1,31]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/924\/907","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/924\/907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T02:35:16Z","timestamp":1485916516000},"score":1,"resource":{"primary":{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,31]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,31]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-924","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1,31]]}}}