{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T23:19:20Z","timestamp":1770679160058,"version":"3.49.0"},"reference-count":0,"publisher":"SRUMB - Romanian Society for Ultrasonography in Medicine and Biology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Ultrason"],"abstract":"<jats:p>Aim: The purpose of the study was to assess the effect of Acoustic Radiation Force Impulse (ARFI) elastography in the\u00a0diagnosis of liver fibrosis in chronic hepatitis B and C patients through Meta-analysis. Material and methods: Four databases\u00a0(PubMed, the Cochrane Library, WanFang data, and CNKI) were searched. The key words were: (\u201cARFI\u201d or \u201cacoustic radiation\u00a0force impulse\u201d) combined with \u201cliver fibrosis\u201d and (\u201cchronic hepatitis\u201d or \u201cHBV HCV\u201d). Heterogeneity (I2) was assessed,\u00a0and its source was analyzed through meta-regression. Results: 21 articles with 2,691 patients were included. The compositeSe=0.79 (95% CI: 0.76-0.83) and Sp=0.86 (95% CI: 0.85-0.88). ARFI elastography showed a better ability to evaluate higherstage\u00a0liver fibrosis and liver cirrhosis (F=3 and F=4, respectively). For F\u22653, Se=0.84 (95% CI: 0.80-0.88, I2=61.37), Sp=0.90 (95% CI: 0.86-0.92, I2=65.10), and AUROC=0.94 (95% CI: 0.91-0.95). Se and Sp and AUROC of F=4 were 0.86 (95% CI:\u00a00.80-0.91, I2=70.67), 0.84 (95% CI: 0.80\u20130.88, I2=78.94) and 0.91 (95% CI: 0.89-0.94), respectively. Besides, the combined RFI values indicate that CHC patients had higher ARFI values especially in the F3 stage (1.87 [95% CI: 1.67-2.06] and 2.31[95% CI: 2.09-2.52] for CHB and CHC, respectively). Conclusion: ARFI elastography is accurate and reliable in the diagnosis\u00a0of CHB- and CHC-induced liver fibrosis and is especially suitable for the evaluation of stages F\u22653 and F=4. CHC patients\u00a0manifest higher ARFI values than CHB patients especially in the F3 stage.<\/jats:p>","DOI":"10.11152\/mu-942","type":"journal-article","created":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T06:18:06Z","timestamp":1482992286000},"page":"23","source":"Crossref","is-referenced-by-count":65,"title":["Acoustic Radiation Force Impulse (ARFI) Elastography for non\u2011invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and meta-analysis"],"prefix":"10.11152","volume":"19","author":[{"given":"Xiangdong","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanyan","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linxue","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4840","published-online":{"date-parts":[[2017,1,31]]},"container-title":["Medical Ultrasonography"],"original-title":[],"link":[{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/942\/899","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/viewFile\/942\/899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T07:35:19Z","timestamp":1485934519000},"score":1,"resource":{"primary":{"URL":"http:\/\/medultrason.ro\/medultrason\/index.php\/medultrason\/article\/view\/942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,31]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,31]]}},"URL":"https:\/\/doi.org\/10.11152\/mu-942","relation":{},"ISSN":["2066-8643","1844-4172"],"issn-type":[{"value":"2066-8643","type":"electronic"},{"value":"1844-4172","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1,31]]}}}