{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:11:59Z","timestamp":1791490319330,"version":"4.3.4"},"reference-count":53,"publisher":"American Vacuum Society","issue":"4","funder":[{"name":"Coordination for the Improvement of Higher Level Personnel","award":["11838-13-2"],"award-info":[{"award-number":["11838-13-2"]}]},{"name":"State of Sao Paulo Research Foundation","award":["2013\/08451-1"],"award-info":[{"award-number":["2013\/08451-1"]}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,12,1]]},"abstract":"<jats:p>The objectives of the present study were to produce bioactive coatings in solutions containing Ca, P, and Si by plasma electrolytic oxidation (PEO) on commercially pure titanium, to investigate the influence of different electrolytes concentration and treatment duration on the produced anodic films and to evaluate biocompatibility properties. The anodic films were characterized using scanning electron microscopy, energy-dispersive spectroscopy, atomic force microscopy, and x-ray diffraction and x-ray photoelectron spectroscopies. The surface energy and roughness were also evaluated. PEO process parameters influenced the crystalline structure formation and surface topography of the anodic films. Higher Ca content produced larger porous (volcanolike appearance) and thicker oxide layers when compared to the lower content. Treatment duration did not produce any topography difference. The treatment modified the surface chemistry, producing an enriched oxide layer with bioactive elements in the form of phosphate compounds, which may be responsible for mimicking bone surface. In addition, a rough surface with increased surface energy was generated. Optimal spreading and proliferation of human mesenchymal stem cells was achieved by PEO treatment, demonstrating excellent biocompatibility of the surface. The main finding is that the biofunctionalization with higher Ca\/P on Ti-surface can improve surface features, potentially considered as a candidate for dental implants.<\/jats:p>","DOI":"10.1116\/1.4932579","type":"journal-article","created":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T00:45:00Z","timestamp":1444265100000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":38,"title":["Incorporation of Ca, P, and Si on bioactive coatings produced by plasma electrolytic oxidation: The role of electrolyte concentration and treatment duration"],"prefix":"10.1116","volume":"10","author":[{"given":"Isabella da Silva Vieira","family":"Marques","sequence":"first","affiliation":[{"name":"University of Campinas (UNICAMP) Department of Prosthodontics and Periodontology, Piracicaba Dental School, , Av Limeira, 901, Piracicaba, S\u00e3o Paulo 13414-903, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilson Cristino","family":"da Cruz","sequence":"additional","affiliation":[{"name":"Univ Estadual Paulista (UNESP) Laboratory of Technological Plasmas, Engineering College, , Av Tr\u00eas de Mar\u00e7o, 511, Sorocaba, S\u00e3o Paulo 18087-180, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Landers","sequence":"additional","affiliation":[{"name":"University of Campinas (UNICAMP) Institute of Physics Gleb Wataghin, , Cidade Universit\u00e1ria Zeferino Vaz, Bar\u00e3o Geraldo, Campinas, S\u00e3o Paulo 13083-859, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy Chia-Chun","family":"Yuan","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago Department of Restorative Dentistry, , College of Dentistry, 801 S Paulina, Chicago, Illinois 60612"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Ferraz","family":"Mesquita","sequence":"additional","affiliation":[{"name":"University of Campinas (UNICAMP) Department of Prosthodontics and Periodontology, Piracicaba Dental School, , Av Limeira, 901, Piracicaba, S\u00e3o Paulo 13414-903, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cortino","family":"Sukotjo","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago Department of Restorative Dentistry, , College of Dentistry, 801 S Paulina, Chicago, Illinois 60612"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathew T.","family":"Mathew","sequence":"additional","affiliation":[{"name":"Rush University Medical Center Department of Orthopedic Surgery, , 1611 W Harrison, Chicago, Illinois 60612"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentim Adelino Ricardo","family":"Bar\u00e3o","sequence":"additional","affiliation":[{"name":"University of Campinas (UNICAMP) Department of Prosthodontics and Periodontology, Piracicaba Dental School, , Av Limeira, 901, Piracicaba, S\u00e3o Paulo 13414-903, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20","published-online":{"date-parts":[[2015,10,7]]},"reference":[{"key":"2023070223484161000_c1","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1002\/jbm.b.33079","volume":"102","year":"2014","journal-title":"J. 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