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A total of 104 patients were involved, with significant findings revealing a reduced incidence of postoperative adverse reactions in the improved PEEK group (28.85%) compared to the conventional PEEK group (50.00%, P\u2009=\u20090.027). Patient satisfaction rates were markedly higher in the improved PEEK cohort (P\u2009&amp;lt;\u20090.05). Although the medical expenses for the enhanced PEEK group were greater (\u00a5 144\u2009600\u2009\u00b1\u200921\u2009200 vs \u00a5 127\u2009400\u2009\u00b1\u200920\u2009100, P\u2009&amp;lt;\u20090.05), there were no notable differences in cerebral blood flow perfusion or survival time between the two groups (P\u2009&amp;gt;\u20090.05). The conclusions indicate that while the enhanced PEEK cranial plates incur higher upfront costs, their benefits in terms of safety and patient satisfaction, along with improved implant stability and bone healing, support their use in clinical practice. Consequently, the upgraded PEEK material is recommended for cranioplasty procedures.<\/jats:p>","DOI":"10.1116\/6.0004208","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T13:20:56Z","timestamp":1740576056000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Clinical study on the application effect of improved polyetheretherketone cranial plate in cranioplasty"],"prefix":"10.1116","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5496-307X","authenticated-orcid":false,"given":"Jiajun","family":"Qin","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University , Shanghai 200072,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5087-4889","authenticated-orcid":false,"given":"Fei","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University , Shanghai 200072,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0101-570X","authenticated-orcid":false,"given":"Jin","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University , Shanghai 200072,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0457-018X","authenticated-orcid":false,"given":"Jiping","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University , Shanghai 200072,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20","published-online":{"date-parts":[[2025,2,26]]},"reference":[{"key":"2025022613205484300_c1","doi-asserted-by":"publisher","first-page":"864385","DOI":"10.3389\/fsurg.2022.864385","volume":"9","year":"2022","journal-title":"Front. 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