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Electrochemical measurements, immersion tests, and cytocompatibility assays consistently confirmed the improved stability and biocompatibility of Cu#BM compared with unmodified Cu. These findings suggest that femtosecond laser-induced surface engineering provides a simple and effective strategy to suppress the early burst release of Cu2+, thereby offering translational potential to reduce clinical side effects associated with Cu-IUDs.<\/jats:p>","DOI":"10.1116\/6.0004923","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:44:28Z","timestamp":1761662668000},"update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Femtosecond laser-textured copper surface for reducing initial copper ion burst release in intrauterine devices"],"prefix":"10.1116","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8567-5966","authenticated-orcid":false,"given":"Junbo","family":"Liu","sequence":"first","affiliation":[{"name":"Affiliated Hospital of Changchun University of Traditional Chinese Medicine 1 Women's Health and Obstetrics Center, , Changchun 130021,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Zhou","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Changchun University of Traditional Chinese Medicine 1 Women's Health and Obstetrics Center, , Changchun 130021,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Changchun University of Traditional Chinese Medicine 1 Women's Health and Obstetrics Center, , Changchun 130021,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuwei","family":"Li","sequence":"additional","affiliation":[{"name":"College of Chemistry, Northeast Normal University 2 , Changchun 130024,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20","published-online":{"date-parts":[[2025,10,28]]},"reference":[{"key":"2025102810442297100_c1","doi-asserted-by":"publisher","first-page":"822.e1","DOI":"10.1016\/j.ajog.2015.08.077","volume":"213","year":"2015","journal-title":"Am. 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