{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:05:47Z","timestamp":1790816747629,"version":"4.1.0"},"reference-count":17,"publisher":"SPIE-Intl Soc Optical Eng","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Opt."],"published-print":{"date-parts":[[2010,5,1]]},"abstract":"<jats:p>Diagnosing sinusitis remains a challenge for primary care physicians. There is a need for a simple, office-based technique to aid in the diagnosis of sinusitis without the cost and radiation risk of conventional radiologic imaging. We designed a low-cost near-infrared (NIR) device to transilluminate the maxillary sinuses. The use of NIR light allows for greater interrogation of deep-tissue structures as compared to visible light. NIR imaging of 21 patients was performed and compared with computed tomography (CT) scans. Individual maxillary sinuses were scored on a scale from 0 to 2 based on their degree of aeration present on CT and similarly based on the NIR signal penetration into the maxilla on NIR images. Our results showed that air-filled and fluid\/tissue-filled spaces can be reasonably distinguished by their differing NIR signal penetration patterns, with average NIR imaging scores for fluid-filled maxillary sinuses (0.93\u00b10.78, n=29) significantly lower than those for normal maxillary sinuses (1.62\u00b10.57, n=13) (p=0.003). NIR imaging of the sinuses is a simple, safe, and cost-effective modality that can potentially aid in the diagnosis of sinusitis. Long-term, significant device refinement and large clinical trials will be needed to determine the diagnostic accuracy of this technique.<\/jats:p>","DOI":"10.1117\/1.3431718","type":"journal-article","created":{"date-parts":[[2010,5,26]],"date-time":"2010-05-26T18:50:42Z","timestamp":1274899842000},"page":"1-5","source":"Crossref","is-referenced-by-count":10,"title":["Near-infrared imaging of the sinuses: preliminary evaluation of a new technology for diagnosing maxillary sinusitis"],"prefix":"10.1117","volume":"15","author":[{"given":"Usama","family":"Mahmood","sequence":"first","affiliation":[{"name":"Univ. of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert E.","family":"Cerussi","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Dehdari","sequence":"additional","affiliation":[{"name":"Univ. of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quoc","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Univ. of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Kelley","sequence":"additional","affiliation":[{"name":"Univ. of California, Irvine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7481-7975","authenticated-orcid":false,"given":"Bruce J.","family":"Tromberg","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6318-7384","authenticated-orcid":false,"given":"Brian J.","family":"Wong","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"189","reference":[{"key":"10.1117\/1.3431718_r1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(03)01397-4"},{"key":"10.1117\/1.3431718_r2","unstructured":"V. Benson and M. A. Marano , \u201cCurrent estimates from the 1993 National Health Interview Survey,\u201d National Center for Health Statistics, Vital Health Stat., 10, 190 (1994)."},{"key":"10.1117\/1.3431718_r3","unstructured":"\u201cNational disease and therapeutic index,\u201d pp. 487\u2013488, IMS Health, Plymouth Meeting, PA (1988\u20131989)."},{"key":"10.1117\/1.3431718_r4","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70001-9"},{"key":"10.1117\/1.3431718_r5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1177\/194589240201600404","volume":"16","author":"Stankiewicz","year":"2002","journal-title":"Am. J. Rhinol.","ISSN":"https:\/\/id.crossref.org\/issn\/1050-6586","issn-type":"print"},{"key":"10.1117\/1.3431718_r6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/194589240301700305","volume":"17","author":"Stankiewicz","year":"2003","journal-title":"Am. J. 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Incaudo , Eds., pp. 3\u201332, Humana Press, Totowa, NJ (1996)."}],"container-title":["Journal of Biomedical Optics"],"original-title":[],"link":[{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-15\/issue-03\/036011\/Near-infrared-imaging-of-the-sinuses--preliminary-evaluation-of\/10.1117\/1.3431718.full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:34:54Z","timestamp":1790814894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-15\/issue-03\/036011\/Near-infrared-imaging-of-the-sinuses--preliminary-evaluation-of\/10.1117\/1.3431718.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,1]]},"references-count":17,"journal-issue":{"issue":"03"},"URL":"https:\/\/doi.org\/10.1117\/1.3431718","relation":{},"ISSN":["1083-3668","1560-2281"],"issn-type":[{"value":"1083-3668","type":"print"},{"value":"1560-2281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,1]]}}}