{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:01:43Z","timestamp":1790208103595,"version":"4.1.0"},"reference-count":22,"publisher":"SPIE-Intl Soc Optical Eng","issue":"02","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"USF Research and Innovation Strategic Investment Pool Awards"},{"name":"USF College of Engineering"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biophoton. Discovery"],"published-print":{"date-parts":[[2025,4,29]]},"abstract":"<jats:p>SignificanceLaser-based phacoemulsification is the preferred treatment for surgical removal of cataracts in the eye. Conventional methods of laser phacoemulsification use expensive, high-powered lasers that use femtosecond pulses to soften and emulsify cataracts, resulting in low- to middle-income countries relying on methods that lead to longer recovery times and higher rates of infection and astigmatism.AimWe introduce and demonstrate the potential of laser phacoemulsification using a millisecond pulsed laser that can be realized using a low-cost diode laser.ApproachWe show proof of concept for this device using computer simulations in COMSOL and with a prototype instrument tested on different tissue-simulating phantoms.ResultsOur experiments show that the millisecond pulsed laser liquifies cataract-like tissues only at the point of illumination.ConclusionsA low-cost device for phacoemulsification can potentially reduce the burden of cataract surgeries in low-resource 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