{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T15:03:35Z","timestamp":1793718215122,"version":"4.6.1"},"reference-count":21,"publisher":"SPIE-Intl Soc Optical Eng","issue":"12","funder":[{"name":"National Institutes of Health","award":["R01EY018184"],"award-info":[{"award-number":["R01EY018184"]}],"id":[{"id":"https:\/\/ror.org\/01cwqze88","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Opt."],"published-print":{"date-parts":[[2015,12,10]]},"abstract":"<jats:p>A custom-built dynamic-focus swept-source optical coherence tomography (SS-OCT) system with a central wavelength of 1310\u00a0nm was used to image the anterior eye from the cornea to the lens. An electrically tunable lens was utilized to dynamically control the positions of focusing planes over the imaging range of 10\u00a0mm. The B-scan images were acquired consecutively at the same position but with different focus settings. The B-scan images were then registered and averaged after filtering the out-of-focus regions using a Gaussian window. By fusing images obtained at different depth focus locations, high-resolution and high signal-strength images were obtained over the entire imaging depth. In vivo imaging of human anterior segment was demonstrated. The performance of the system was compared with two commercial OCT systems. The human eye ciliary body was better visualized with the dynamic-focusing SS-OCT system than using the commercial 840 and 1310\u00a0nm OCT systems. The sulcus-to-sulcus distance was measured, and the result agreed with that acquired with ultrasound biomicroscopy.<\/jats:p>","DOI":"10.1117\/1.jbo.20.12.126002","type":"journal-article","created":{"date-parts":[[2015,12,10]],"date-time":"2015-12-10T12:31:08Z","timestamp":1449750668000},"page":"1-7","source":"Crossref","is-referenced-by-count":22,"title":["Imaging the anterior eye with dynamic-focus swept-source optical coherence tomography"],"prefix":"10.1117","volume":"20","author":[{"given":"Johnny P.","family":"Su","sequence":"first","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maolong","family":"Tang","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Liu","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex D.","family":"Pechauer","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6360-0121","authenticated-orcid":false,"given":"David","family":"Huang","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Oregon Health & Science Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"189","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.05.025"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.059535"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2008.01892.x"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1126\/science.1957169"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305218"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.4.000466"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1364\/OE.17.008947"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1364\/OE.18.003632"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.20.1.016012"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0105224"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.5.001877"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1364\/OE.22.031746"},{"key":"r13","article-title":"Improved visualization of the vitreous using swept source optical coherence tomography with dynamic focus sweeping","author":"Spaide","year":"2014"},{"key":"r14","article-title":"American National Standard for safe use of lasers","year":"2014"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.5.002931"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1364\/OE.23.009824"},{"key":"r17","first-page":"39","article-title":"Interpretation of corneal images","author":"Huang","year":"2010"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1364\/OE.11.000889"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1364\/OL.28.002067"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1364\/OE.11.002183"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2003.12.043"}],"container-title":["Journal of Biomedical Optics"],"original-title":[],"link":[{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-20\/issue-12\/126002\/Imaging-the-anterior-eye-with-dynamic-focus-swept-source-optical\/10.1117\/1.JBO.20.12.126002.full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:04:43Z","timestamp":1790816683000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-20\/issue-12\/126002\/Imaging-the-anterior-eye-with-dynamic-focus-swept-source-optical\/10.1117\/1.JBO.20.12.126002.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,10]]},"references-count":21,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.1117\/1.jbo.20.12.126002","relation":{},"ISSN":["1083-3668","1560-2281"],"issn-type":[{"value":"1083-3668","type":"print"},{"value":"1560-2281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,10]]}}}