{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:38:56Z","timestamp":1793299136165,"version":"4.5.0"},"reference-count":0,"publisher":"SPIE-Intl Soc Optical Eng","issue":"04","license":[{"start":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T00:00:00Z","timestamp":1618012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Opt."],"published-print":{"date-parts":[[2021,4,10]]},"abstract":"<jats:p>Significance: Digital holographic microscopy is widely used to get the quantitative phase information of transparent cells.\nAim: However, the sample phase is superimposed with aberrations. To quantify the phase information, aberrations need to be fully compensated.\nApproach: We propose a technique to obtain aberration-free phase imaging, using the derivative-based principal component analysis (dPCA).\nResults: With dPCA, almost all aberrations can be extracted and compensated without requirements on background segmentation, making it efficient and convenient.\nConclusions: It solves the problem that the conventional principal component analysis (PCA) algorithm cannot compensate the common but intricate higher order cross-term aberrations, such as astigmatism and coma. Moreover, the dPCA strategy proposed here is not only suitable for aberration compensation but also applicable for other cases where there exist cross-terms that cannot be analyzed with the PCA algorithm.<\/jats:p>","DOI":"10.1117\/1.jbo.26.4.046501","type":"journal-article","created":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T03:08:35Z","timestamp":1618024115000},"page":"1-11","source":"Crossref","is-referenced-by-count":11,"title":["Aberration-free digital holographic phase imaging using the derivative-based principal component analysis"],"prefix":"10.1117","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0575-0268","authenticated-orcid":false,"given":"Xiaomin","family":"Lai","sequence":"first","affiliation":[{"name":"Hangzhou Dianzi Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8959-2388","authenticated-orcid":false,"given":"Sheng","family":"Xiao","sequence":"additional","affiliation":[{"name":"Boston Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2593-7687","authenticated-orcid":false,"given":"Chen","family":"Xu","sequence":"additional","affiliation":[{"name":"Hangzhou Dianzi Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanhui","family":"Fan","sequence":"additional","affiliation":[{"name":"Hangzhou Dianzi Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaihua","family":"Wei","sequence":"additional","affiliation":[{"name":"Hangzhou Dianzi Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"189","container-title":["Journal of Biomedical Optics"],"original-title":[],"link":[{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-26\/issue-04\/046501\/Aberration-free-digital-holographic-phase-imaging-using-the-derivative-based\/10.1117\/1.JBO.26.4.046501.full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:33:38Z","timestamp":1790271218000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-26\/issue-04\/046501\/Aberration-free-digital-holographic-phase-imaging-using-the-derivative-based\/10.1117\/1.JBO.26.4.046501.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,10]]},"references-count":0,"journal-issue":{"issue":"04"},"URL":"https:\/\/doi.org\/10.1117\/1.jbo.26.4.046501","relation":{},"ISSN":["1083-3668","1560-2281"],"issn-type":[{"value":"1083-3668","type":"print"},{"value":"1560-2281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,10]]}}}