{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T15:16:52Z","timestamp":1792336612471,"version":"4.4.0"},"reference-count":34,"publisher":"SPIE-Intl Soc Optical Eng","issue":"05","license":[{"start":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T00:00:00Z","timestamp":1706313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Opt."],"published-print":{"date-parts":[[2024,1,27]]},"abstract":"<jats:p>SignificancePreterm birth is defined as a birth before 37 weeks of gestation and is one of the leading contributors to infant mortality rates globally. Premature birth can lead to life-long developmental impairment for the child. Unfortunately, there is a significant lack of tools to diagnose preterm birth risk, which limits patient care and the development of new therapies.AimTo develop a speculum-free, portable preterm imaging system (PPRIM) for cervical imaging; testing of the PPRIM system to resolve polarization properties of birefringent samples; and testing of the PPRIM under an IRB on healthy, non-pregnant volunteers for visualization and polarization analysis of cervical images.ApproachThe PPRIM can perform 4\u00d73 Mueller-matrix imaging to characterize the remodeling of the uterine cervix during pregnancy. The PPRIM is built with a polarized imaging probe and a flexible insertable sheath made with a compatible flexible rubber-like material to maximize comfort and ease of use.ResultsThe PPRIM device is developed to meet specific design specifications as a speculum-free, portable, and comfortable imaging system with polarized imaging capabilities. This system comprises a main imaging component and a flexible silicone inserter. The inserter is designed to maximize comfort and usability for the patient. The PPRIM shows high-resolution imaging capabilities at the 20\u00a0mm working distance and 25\u00a0mm circular field of view. The PPRIM demonstrates the ability to resolve birefringent sample orientation and full field capture of a healthy, non-pregnant cervix.ConclusionThe development of the PPRIM aims to improve access to the standard of care for women\u2019s reproductive health using polarized Mueller-matrix imaging of the cervix and reduce infant and maternal mortality rates and better quality of life.<\/jats:p>","DOI":"10.1117\/1.jbo.29.5.052918","type":"journal-article","created":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T12:41:48Z","timestamp":1706359308000},"page":"1-14","source":"Crossref","is-referenced-by-count":6,"title":["Speculum-free portable preterm imaging system"],"prefix":"10.1117","volume":"29","author":[{"given":"Tananant","family":"Boonya-ananta","sequence":"first","affiliation":[{"name":"Florida International 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