{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:25:32Z","timestamp":1792787132348,"version":"4.5.0"},"reference-count":48,"publisher":"SPIE-Intl Soc Optical Eng","issue":"04","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Cure for Cancer Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Opt."],"published-print":{"date-parts":[[2025,4,4]]},"abstract":"<jats:p>SignificanceBladder cancer (BC) diagnosis, management, and outcomes depend on the accurate detection of tumors via optical technologies. Accordingly, understanding the benefits and limitations of these technologies permits improvements in patient care and identifies areas for future research.AimWe outline the current process of BC detection and diagnosis, explore the current role of optical technologies, and discuss the opportunities and challenges they present in this field.ApproachThe current diagnostic pathway of BC, the use of optical technologies, and their shortcomings in this process are reviewed. From there, opportunities and challenges of optics in BC detection and diagnosis are discussed.ResultsBC management is expensive due to the limitations of white light cystoscopy, the requirement for histopathological confirmation, and the need for long-term surveillance. Alternative non-optical methods lack accuracy, and available optical techniques focus only on cancer detection. Alternatives to histopathology need to provide accurate real-time results to be effective. Optical advancements offer potential benefits; however, challenges include cost-effectiveness, device complexity, required training, and tumor heterogeneity.ConclusionsOptical techniques could accelerate BC diagnosis, reduce costs, and enable alternative treatments. However, overcoming technical and practical challenges is essential for their successful integration.<\/jats:p>","DOI":"10.1117\/1.jbo.30.4.040601","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T13:13:50Z","timestamp":1743772430000},"page":"1-8","source":"Crossref","is-referenced-by-count":4,"title":["Perspective on the use of optics in bladder cancer detection and diagnosis"],"prefix":"10.1117","volume":"30","author":[{"given":"Marinka J.","family":"Remmelink","sequence":"first","affiliation":[{"name":"Amsterdam UMC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan J.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Stanford Univ. School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakko A.","family":"Nieuwenhuijzen","sequence":"additional","affiliation":[{"name":"Amsterdam UMC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5642-1133","authenticated-orcid":false,"given":"Ton G.","family":"van Leeuwen","sequence":"additional","affiliation":[{"name":"Amsterdam UMC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph C.","family":"Liao","sequence":"additional","affiliation":[{"name":"Stanford Univ. School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3047-3637","authenticated-orcid":false,"given":"Daniel  M.","family":"de Bruin","sequence":"additional","affiliation":[{"name":"Amsterdam UMC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"189","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2021.08.010"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00744-3"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-023-04428-6"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1089\/end.2005.19.861"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1080\/21681805.2020.1782978"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2016.0246"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16010160"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.04.015"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.08.024"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.01.006"},{"key":"r11","article-title":"Dbc-zorgproducten","year":"2024"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.03.044"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.5173\/ceju.2016.893"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics10090703"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2017.12.001"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1002\/mp.12510"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-021-07765-5"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07153-5"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.22763"},{"key":"r20","first-page":"388","article-title":"Technique of transurethral needle core biopsy to confirm invasive bladder cancer staging","author":"Ch\u0142osta","year":"2010"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1080\/003655901750425837"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1007\/BF02893372"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000401)88:7<1663::AID-CNCR21>3.0.CO;2-8"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000003846"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.07317.x"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196412)17:12<1528::AID-CNCR2820171203>3.0.CO;2-#"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.120"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.08.091"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00470"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2022.103220"},{"key":"r31","article-title":"Flexible video cystoscope HD-VIEW","year":"2024"},{"key":"r32","article-title":"Products of urology","year":"2024"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-009-0395-z"},{"key":"r34","first-page":"928","article-title":"Confocal laser endomicroscopy","year":"2014"},{"key":"r35","doi-asserted-by":"publisher","DOI":"10.1111\/bju.16471"},{"key":"r36","doi-asserted-by":"publisher","DOI":"10.1089\/end.2019.0354"},{"key":"r37","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3180588283"},{"key":"r38","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-022-00565-0"},{"key":"r39","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23079"},{"key":"r40","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.04.117"},{"key":"r41","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-1683(24)00099-5"},{"key":"r42","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-023-02900-7"},{"key":"r43","doi-asserted-by":"publisher","DOI":"10.1089\/end.2023.0056"},{"key":"r44","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.08.032"},{"key":"r45","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-024-00904-9"},{"key":"r46","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28408"},{"key":"r47","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20200116"},{"key":"r48","article-title":"Wetenschappelijk onderzoek - BladParadigm: de Blaaskanker Paradigma studie"}],"container-title":["Journal of Biomedical Optics"],"original-title":[],"link":[{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-30\/issue-04\/040601\/Perspective-on-the-use-of-optics-in-bladder-cancer-detection\/10.1117\/1.JBO.30.4.040601.full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:19:22Z","timestamp":1790205562000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-biomedical-optics\/volume-30\/issue-04\/040601\/Perspective-on-the-use-of-optics-in-bladder-cancer-detection\/10.1117\/1.JBO.30.4.040601.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,4]]},"references-count":48,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2025,4,1]]}},"URL":"https:\/\/doi.org\/10.1117\/1.jbo.30.4.040601","relation":{},"ISSN":["1083-3668","1560-2281"],"issn-type":[{"value":"1083-3668","type":"print"},{"value":"1560-2281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,4]]}}}