{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:07:33Z","timestamp":1790208453237,"version":"4.1.0"},"reference-count":40,"publisher":"SPIE-Intl Soc Optical Eng","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Imag."],"published-print":{"date-parts":[[2024,8,10]]},"abstract":"<jats:p>PurposeSpatio-temporal variability in clinical fluoroscopy and cine angiography images combined with nonlinear image processing prevents the application of traditional image quality measurements in the cardiac catheterization laboratory. We aimed to develop and validate methods to measure human observer impressions of the image quality.ApproachMulti-frame images of the thorax of a euthanized pig were acquired to provide an anatomical background. The detector dose was varied from 6 to 200\u00a0nGy (increments 2\u00d7), and 0.6 and 1.0\u00a0mm focal spots were used. Two coronary stents with\/without 0.5\u00a0mm separation and a synthetic right coronary artery (RCA) with hemispherical defects were embedded into the background images as test objects. The quantitative observer (n=17) performance was measured using a two-alternating forced-choice test of whether stents were separated and by a count of visible right coronary artery defects. Qualitative impressions of noise, spatial resolution, and overall image quality were measured using a visual analog scale (VAS). A paired t-test and multinomial logistic regression model were used to identify statistically significant factors affecting the observer\u2019s impression image quality.ResultsThe proportion of correct detection of stent separation and the number of reported right coronary artery defects changed significantly with detector dose increment in the 6 to 100\u00a0nGy (p&lt;0.05). Although a trend favored the 0.6 versus 1.0\u00a0mm focal spot for these quantitative assessments, this was insignificant. Visual analog scale measurements changed significantly with detector dose increments in the range of 24 to 100\u00a0nGy and focal spot size (p&lt;0.05). The application of multinomial logistic regression analysis to observer VAS scores demonstrated sensitivity matching of the paired t-test applied to quantitative observer performance measurements.ConclusionsBoth quantitative and qualitative measurements of observer impression of the image quality were sensitive to image quality changes associated with changing the detector dose and focal spot size. These findings encourage future work that uses qualitative image quality measurements to assess clinical fluoroscopy and angiography image quality.<\/jats:p>","DOI":"10.1117\/1.jmi.11.4.045502","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T08:28:21Z","timestamp":1723278501000},"page":"1-21","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of human observer impression of X-ray fluoroscopy and angiography image quality with technical changes to image quality"],"prefix":"10.1117","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1608-0637","authenticated-orcid":false,"given":"Jelena M.","family":"Mihailovic","sequence":"first","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihisa","family":"Kanaji","sequence":"additional","affiliation":[{"name":"Mayo 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