{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:55:15Z","timestamp":1790895315368,"version":"4.1.0"},"reference-count":30,"publisher":"SPIE-Intl Soc Optical Eng","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Imag."],"published-print":{"date-parts":[[2016,3,8]]},"abstract":"<jats:p>Exposed root surfaces due to gingival recession are subject to biofilm stagnation that can result in caries formation. Cervical enamel and dentin demineralization induced by a cariogenic biofilm was evaluated using swept-source optical coherence tomography (SS-OCT). The cementoenamel junction (CEJ) sections of extracted human teeth were subjected to demineralization for 1, 2, or 3 weeks. A suspension of Streptococcus mutans was applied to form a cariogenic biofilm using an oral biofilm reactor. After incubation, demineralization was observed by SS-OCT. For the analysis of SS-OCT signal, the value of the area under the curve (AUC) of the signal profile was measured. Statistical analyses were performed with 95% level of confidence. Cervical demineralization was displayed as a bright zone in SS-OCT. The demineralization depth of dentin was significantly deeper than that of enamel (p&lt;0.05). Enamel near the CEJ demonstrated a significant increase of AUC over the other enamel region after the demineralization. The gaps along the dentinoenamel junction were additionally observed in SS-OCT. SS-OCT was capable of monitoring the cervical demineralization induced by a cariogenic biofilm and is considered to be a promising modality for the diagnosis of cervical demineralization.<\/jats:p>","DOI":"10.1117\/1.jmi.3.1.014504","type":"journal-article","created":{"date-parts":[[2016,3,8]],"date-time":"2016-03-08T12:30:57Z","timestamp":1457440257000},"page":"1-7","source":"Crossref","is-referenced-by-count":8,"title":["Assessment of cervical demineralization induced by Streptococcus mutans using swept-source optical coherence tomography"],"prefix":"10.1117","volume":"3","author":[{"given":"Hiroki","family":"Tezuka","sequence":"first","affiliation":[{"name":"Tokyo Medical and Dental Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Shimada","sequence":"additional","affiliation":[{"name":"Tokyo Medical and Dental Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khairul","family":"Matin","sequence":"additional","affiliation":[{"name":"Tokyo Medical and Dental Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaomi","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Tokyo Medical and Dental Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Sadr","sequence":"additional","affiliation":[{"name":"Univ. of Washington School of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunori","family":"Sumi","sequence":"additional","affiliation":[{"name":"National Ctr. for Geriatrics and Gerontology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Tagami","sequence":"additional","affiliation":[{"name":"Tokyo Medical and Dental Univ."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"189","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2007.10.010"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12094"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690051801"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2010.01284.x"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2012.04.004"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.26.613"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5712(03)00009-5"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2012.10.007"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201200210"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-014-1541-4"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2011.05.003"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2011.01.011"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.26.915"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22292"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201100014"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201200012"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201400113"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1117\/1.3600448"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1100\/2012\/587254"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1016\/S0109-5641(99)00020-2"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2010.11.009"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1177\/08959374960100021801"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1007\/s10853-012-6693-7"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-008-9212-8"},{"key":"r25","first-page":"585","article-title":"Shear bond strength of current adhesive systems to enamel, dentin and dentin-enamel junction region","author":"Shimada","year":"2003"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690052001"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.05.008"},{"key":"r28","first-page":"1072","article-title":"Structure-property relations and crack resistance at the bovine dentin-enamel junction","author":"Lin","year":"1994"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(97)00131-0"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514557330"}],"container-title":["Journal of Medical Imaging"],"original-title":[],"link":[{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-medical-imaging\/volume-3\/issue-01\/014504\/Assessment-of-cervical-demineralization-induced-by-Streptococcus-mutans-using-swept\/10.1117\/1.JMI.3.1.014504.full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:11:19Z","timestamp":1790892679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spiedigitallibrary.org\/journals\/journal-of-medical-imaging\/volume-3\/issue-01\/014504\/Assessment-of-cervical-demineralization-induced-by-Streptococcus-mutans-using-swept\/10.1117\/1.JMI.3.1.014504.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,8]]},"references-count":30,"journal-issue":{"issue":"01"},"URL":"https:\/\/doi.org\/10.1117\/1.jmi.3.1.014504","relation":{},"ISSN":["2329-4302","2329-4310"],"issn-type":[{"value":"2329-4302","type":"print"},{"value":"2329-4310","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,8]]}}}