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The projections are based on a surface sampling of the anatomical structures. On top of the MLC mechanical constraints, verification constraints are imposed on the MLC segments, in order to get reliable dosimetry using a commercial dose calculation engine. Thus, in each direction, the aperture's cross\u2010section must be greater than a specified threshold, in our case 2 cm. Furthermore, junctions are not tolerated in order to avoid underdosage, for instance from the tongue\u2010and\u2010groove effect. The use of such MLC fields simplifies the verification process. The performance of the algorithm is illustrated for head and neck, thorax and prostate cases. Only a fraction of a second of CPU time is required to perform the segmentation for each beam.<\/jats:p>","DOI":"10.1118\/1.1697670","type":"journal-article","created":{"date-parts":[[2004,7,2]],"date-time":"2004-07-02T15:15:11Z","timestamp":1088781311000},"page":"1539-1545","source":"Crossref","is-referenced-by-count":15,"title":["Automatic generation of anatomy\u2010based MLC fields in aperture\u2010based IMRT"],"prefix":"10.1002","volume":"31","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Beaulieu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Beaulieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Tremblay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Lachance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,5,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00082-0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01727-8"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1477415"},{"key":"e_1_2_1_5_1","first-page":"1337","article-title":"Optimizing beam orientations and virtual wedges in multifield conformal radiotherapy","volume":"29","author":"Beaulieu F.","year":"2002","journal-title":"Med. 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