{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:12:09Z","timestamp":1792509129557,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,11,24]],"date-time":"2004-11-24T00:00:00Z","timestamp":1101254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>The influence of antiscatter x\u2010ray grids on image quality in cone\u2010beam computed tomography (CT) is evaluated through broad experimental investigation for various anatomical sites (head and body), scatter conditions (scatter\u2010to\u2010primary ratio (SPR) ranging from <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0001.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0001\"\/> to 150%), patient dose, and spatial resolution in three\u2010dimensional reconstructions. Studies involved linear grids in combination with a flat\u2010panel imager on a system for kilovoltage cone\u2010beam CT imaging and guidance of radiation therapy. Grids were found to be effective in reducing x\u2010ray scatter \u201ccupping\u201d artifacts, with heavier grids providing increased image uniformity. The system was highly robust against ring artifacts that might arise in CT reconstructions as a result of gridline shadows in the projection data. The influence of grids on soft\u2010tissue detectability was evaluated quantitatively in terms of absolute contrast, voxel noise, and contrast\u2010to\u2010noise ratio (CNR) in cone\u2010beam CT reconstructions of <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0002.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0002\"\/> \u201chead\u201d and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0003.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0003\"\/> \u201cbody\u201d cylindrical phantoms. Imaging performance was investigated qualitatively in observer preference tests based on patient images (pelvis, abdomen, and head\u2010and\u2010neck sites) acquired with and without antiscatter grids. The results suggest that although grids reduce scatter artifacts and improve subject contrast, there is little strong motivation for the use of grids in cone\u2010beam CT in terms of CNR and overall image quality under most circumstances. The results highlight the tradeoffs in contrast and noise imparted by grids, showing improved image quality with grids only under specific conditions of high x\u2010ray scatter <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0004.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0004\"\/>, high imaging dose <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0005.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0005\"\/>, and low spatial resolution (voxel size <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mp9789-math-0006.png\" xlink:title=\"urn:x-wiley:00942405:media:mp9789:mp9789-math-0006\"\/>).<\/jats:p>","DOI":"10.1118\/1.1819789","type":"journal-article","created":{"date-parts":[[2004,12,7]],"date-time":"2004-12-07T23:01:54Z","timestamp":1102460514000},"page":"3506-3520","source":"Crossref","is-referenced-by-count":202,"title":["The influence of antiscatter grids on soft\u2010tissue detectability in cone\u2010beam computed tomography with flat\u2010panel detectors"],"prefix":"10.1002","volume":"31","author":[{"given":"J. H.","family":"Siewerdsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Moseley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bakhtiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Richard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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