{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T12:15:54Z","timestamp":1793621754286,"version":"4.5.0"},"reference-count":62,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2007,11,15]],"date-time":"2007-11-15T00:00:00Z","timestamp":1195084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2007,12]]},"abstract":"The image quality and localization accuracy for C\u2010arm tomosynthesis and cone\u2010beam computed tomography (CBCT) guidance of head and neck surgery were investigated. A continuum in image acquisition was explored, ranging from a single exposure (radiograph) to multiple projections acquired over a limited arc (tomosynthesis) to a full semicircular trajectory (CBCT). Experiments were performed using a prototype mobile C\u2010arm modified to perform 3D image acquisition (a modified Siemens PowerMobil). The tradeoffs in image quality associated with the extent of the source\u2010detector arc , the number of projection views, and the total imaging dose were evaluated in phantom and cadaver studies. Surgical localization performance was evaluated using three cadaver heads imaged as a function of . Six localization tasks were considered, ranging from high\u2010contrast feature identification (e.g., tip of a K\u2010wire pointer) to more challenging soft\u2010tissue delineation (e.g., junction of the hard and soft palate). Five head and neck surgeons and one radiologist participated as observers. For each localization task, the 3D coordinates of landmarks pinpointed by each observer were analyzed as a function of . For all tomosynthesis angles, image quality was highest in the coronal plane, whereas sagittal and axial planes exhibited a substantial decrease in spatial resolution associated with out\u2010of\u2010plane blur and distortion. Tasks involving complex, lower\u2010contrast features demonstrated steeper degradation with smaller tomosynthetic arc. Localization accuracy in the coronal plane was correspondingly high, maintained to down to , whereas sagittal and axial localization degraded rapidly below . Similarly, localization precision was better than within the coronal plane, compared to out\u2010of\u2010plane for tomosynthesis angles below . An overall 3D localization accuracy of was achieved with for most tasks. The high in\u2010plane spatial resolution, short scanning time, and low radiation dose characteristic of tomosynthesis may enable the surgeon to collect near real\u2010time images throughout the procedure with minimal interference to surgical workflow. Therefore, tomosynthesis could provide a useful addition to the image\u2010guided surgery arsenal, providing on\u2010demand, high quality image updates, complemented by CBCT at critical milestones in the surgical procedure.<\/jats:p>","DOI":"10.1118\/1.2799492","type":"journal-article","created":{"date-parts":[[2007,12,6]],"date-time":"2007-12-06T23:48:18Z","timestamp":1196984898000},"page":"4664-4677","source":"Crossref","is-referenced-by-count":69,"title":["Image quality and localization accuracy in C\u2010arm tomosynthesis\u2010guided head and neck surgery"],"prefix":"10.1002","volume":"34","author":[{"given":"G.","family":"Bachar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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